Publications by authors named "Florence Ponsonnailles"
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Synopsis of recent research by authors named "Florence Ponsonnailles"
- Florence Ponsonnailles' research primarily focuses on the mechanisms of drug resistance in cancer therapy, particularly related to the efficacy of platinum-based treatments such as Cisplatin in Non-Small-Cell Lung Cancer (NSCLC).
- Her studies emphasize the roles of specific proteins, like ERCC1 and USP1, in the DNA damage response (DDR) pathways, and their implications for enhancing treatment outcomes and overcoming resistance to chemotherapy.
- Ponsonnailles also investigates the prognostic value of various isoforms of ERCC1, aiming to establish reliable biomarkers for predicting patient responses to DNA damaging agents in cancer treatments, highlighting the need for standardized evaluation methods across clinical trials.
