Publications by authors named "Florence Michard"

Introduction: Transgender identity is poorly accepted in France, and data on living conditions and the daily difficulties transgender people encounter are scarce. This lack of data reinforces their invisibility in social life, contributes to their stigmatisation and probably increases the burden of HIV infection, especially for HIV-positive transgender people (TRHIV). The main objective of the community-based research study ANRS Trans&HIV is to identify personal and social situations of vulnerability in TRHIV, the obstacles they encounter in terms of access to and retention in medical care, and their gender affirmation and HIV care needs.

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Objectives: The principal outcome was to describe clinical characteristics of a transgender male-to-female (TGW) cohort followed for pre-exposure HIV prophylaxis (PrEP).

Introduction: Few efforts and preventive interventions have targeted transgender population, despite them being at great risk of HIV infection.

Methods: This was a retrospective transgender male-to-female (TGW) cohort followed for PrEP at Bichat Hospital Sexual Health Clinic between February 2016 and January 2019.

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Article Synopsis
  • In utero transmission of Leishmania infantum is suggested as the cause of congenital leishmaniasis, but research is still limited.
  • There is a need for more data to understand the impacts on infant development.
  • This report details a case of a newborn affected by congenital leishmaniasis, linked to a mother who was also HIV-positive, documenting significant liver and neurological issues at birth.
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Male-to-female transgender (MtF TG) individuals often report using illegal subcutaneous silicone injections for body feminisation. It leads to silicone dissemination and various dermatologic complications.We report the long-term complications of these feminisation procedures with blood smear examination and dermatologic examination.

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Article Synopsis
  • - The study examines the health issues faced by HIV-infected transwomen compared to HIV-infected cisgender men, focusing on metabolic syndrome, thyroid, and adrenal functions.
  • - Results showed that while the prevalence of metabolic syndrome was similar between the two groups, transwomen had significantly higher rates of subclinical hypothyroidism (12% vs. 3%) and adrenal insufficiency (20% vs. 8%).
  • - The findings indicate that although hormonal consumption was common among transwomen, it did not affect antiretroviral drug effectiveness; however, regular assessment of thyroid and adrenal functions is recommended for this population.
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Salvage therapy including foscarnet (PFA), zidovudine (ZDV) and an optimized background ART (OBT) has been shown to be effective in patients with advanced HIV infection, and no therapeutic options. Dolutegravir (DTG) may offer a more active combination. Objective was to describe efficacy and tolerability of PFA-ZDV-DTG containing regimen.

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