Publications by authors named "Florence Julien-Marsollier"

Article Synopsis
  • * The study found that MSCs influence microglia, the brain's immune cells, to adopt pro-regenerative functions by altering the extracellular matrix in response to inflammation.
  • * Key findings showed that MSC secretome leads to changes in microglial behavior, enhancing their mobility and cellular structures, which are important for promoting healing in the brain.
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Background: For many years, blood-saving techniques and the enhanced recovery after surgery approach have been used to optimise the quality of care and shorten hospital stays. The creation of dedicated spine teams combining surgeons and anaesthesiologists specialised in spine surgery has been proven beneficial in adults. The objective of this study was to determine whether involving a spine team in the management of paediatric patients with scoliosis treated by posterior spinal fusion was associated with shorter hospital stays.

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Background: The administration of intravenous lidocaine during the peri-operative period may improve pain management after paediatric surgery.

Objective: To explore the decrease in postoperative pain intensity and opioid consumption associated with peri-operative lidocaine administration in the paediatric population.

Design: A systematic review with meta-analysis of randomised controlled trials and a Grading of Recommendations Assessment, Development and Evaluation (GRADE) analysis.

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Purpose: Hybrid techniques using thoracic sublaminar bands have proved their efficacy in adolescent idiopathic scoliosis posterior fusion, but clinical axial correction sometimes remained disappointing. One solution found was "the frame technique" and the second alternative was the replacement of the convex sublaminar bands by periapical uniplanar screws. The goal of this study was to compare clinical and radiological outcomes of both techniques in a consecutive cohort of adolescent idiopathic scoliosis patients.

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  • Same-day discharge after cholecystectomy is becoming common in both adults and children, yet there's a gap in teaching models for pediatric procedures; this study aimed to evaluate clinical outcomes using an Enhanced Recovery After Surgery (ERAS) protocol for pediatric patients undergoing laparoscopic cholecystectomy.
  • Implemented in 2015, the ERAS pathway focused on optimizing various aspects of surgery, such as admission, anesthesia, and postoperative care, with clear guidelines on when day-case surgery was unsuitable due to specific medical conditions.
  • Among 33 pediatric patients analyzed from 2015 to 2020, only one intraoperative complication occurred, with 9% needing an overnight stay, while no significant postoperative issues were reported, highlighting
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  • This study focuses on the challenges of bleeding and blood transfusion during scoliosis surgery, particularly examining how factors like intraoperative fluid intake affect the need for blood transfusions in adolescents with scoliosis.!* -
  • Conducted over two years with 200 patients, the research identified that a higher volume of intraoperative crystalloid fluid significantly predicts the likelihood of requiring allogenic blood transfusions.!* -
  • The findings suggest a link between increased crystalloid intake and transfusion risk, recommending further studies to explore the direct cause-and-effect relationship between fluid management and blood transfusion needs in these surgeries.!*
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Background: Congenital pulmonary airway malformation (CPAM) is the most common pulmonary malformation. It can be managed via thoracoscopic lobectomy, which is safe and advantageous over thoracotomy. Some authors advocate the need for early resection to get an advantage over lung growth.

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Purpose: Patient blood management has been recently emphasized to avoid perioperative blood transfusion in AIS surgery. Hydroxyapatite charged collagen sponge (HCS) is a bone substitute material made of collagen and ceramized hydroxyapatite, with associated haemostatic properties. The goal of this study was to assess the impact of HCS in the perioperative blood loss in AIS surgery.

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Introduction: Cosmetic concerns are one of the main complaints of patients with adolescent idiopathic scoliosis (AIS). Several studies have shown a significant improvement in self-image scores after thoracoplasty. However, the effects of thoracoplasty on pulmonary function and clinical outcomes remain debated.

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Introduction: Neonatal and infant anaesthesia are associated with a high risk of perioperative complications. The aim of the current study was to describe those risks in France using the French data from the NECTARINE study.

Material And Methods: Data from the French centres that participated to the NECTARINE study were analysed.

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Background: Correcting pelvic obliquity is among the main goals of surgery for neuromuscular scoliosis. Spino-pelvic fixation must be stable and capable of withstanding the considerable mechanical forces applied at the lumbo-sacral junction. Selection of the best anchoring option is therefore crucial.

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Background: The goal of the present study was to investigate intraoperative factors associated with major neurological complications at 1 year following surgery for necrotizing enterocolitis.

Material And Methods: The study consisted of a retrospective review of medical charts of patients operated for over one calendar year in one institution. Data collected included demographic data, cardiac resuscitation at birth, Bell classification, antibiotics usage, time of day of surgery, surgical technique, surgical duration, type of ventilation, intraoperative vasoactive agents, and albumin use, nadir cerebral saturation, the decrease in cerebral saturation from baseline, the time period when cerebral saturation was at least 20% below baseline, and the mean arterial pressure at nadir cerebral saturation.

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Introduction: Lockdown involved strict confinement of children at home, radically affecting their way of life, with increased risk of domestic accidents and the temptation to step outside of the legal framework. The aim of the present study was to analyze the impact of lockdown on pediatric emergency turnover in a university reference center situated in a high-risk "red zone" and to describe specific management measures.

Hypothesis: Pediatric emergency turnover and the corresponding lesion mechanisms were altered by lockdown.

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Purpose: Definitive fusion can be considered in early onset scoliosis (EOS) around triradiate cartilage closure. Halo-gravity traction (HGT) is an old strategy that can help lengthen and balance the spine before fusion. The postoperative changes of the trunk have never been investigated to date with modern imaging.

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Article Synopsis
  • Opioid-reduced anesthesia (ORA) was proposed to lower morphine use and chronic pain in adolescents undergoing surgery for idiopathic scoliosis (AIS).
  • A study compared two groups: one using traditional opioid-based anesthesia and the other using ORA, focusing primarily on morphine usage on the first day post-surgery.
  • Results showed that the ORA group used significantly less morphine and experienced less persistent neuropathic pain after one year compared to the control group.
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Background: The objective of this study was to measure the incidence of arterial oxygen desaturation during rapid sequence induction intubation in children following apnoeic oxygenation via transnasal humidified rapid-insufflation ventilatory exchange (THRIVE).

Methods: In this prospective observational study, arterial desaturation < 95% SaO before intubation was recorded following apnoeic RSI combining an intravenous hypnotic agent, suxamethonium and THRIVE (used during the apnoeic period). The incidence of desaturation was calculated in the whole cohort and according to patients' age (older or younger than 1 year).

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Background: Little evidence is available regarding work-related quality of life (WRQoL) for anesthesiologists. We aimed to explore factors associated with WRQoL among French anesthesiologists.

Methods: The study surveyed French anesthesiologists qualified for more than 2 years.

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