NEURODEM: assessment of the iatrogenic alert indicator for nursing home patients with Alzheimer's or Alzheimer-like disease.

Introduction: Neuroleptics are known to induce Parkinsonism, tardive dyskinesia and their long-term use was associated with increased risk of hip fractures and impaired cognitive function and even death.

Methods: The primary objective of Neurodem study was to determine the IAI of patients with Alzheimer's disease in French NH.

Results: 1022 patients were enrolled.

[Is there any predictive factors for hospital admission of elder subjects from nursing home?].

Background And Aim: Hospitalizations of elderly people are responsible for psychological and physical unbalance and must be limited. The aim of the study is to determinate if there are predictive factors of hospitalizations in emergency for institutionalized patients.

Patients And Method: It is a controlled study of 12 months about hospitalizations in emergency from nursing homes.

[Validation of a screening tool toward a geriatric comprehensive assessment during a non geriatric consultation: the geriatric warning test].

Comprehensive geriatric assessment (CGA) is a validated method but is time consuming and must be performed by several professional. It is useful to elaborate a screening tool, which allows the elderly to CGA. The aim of this study is to validate the Geriatric Warning Test (GWT), a 6-questions form: 1) Did your patient consult or did hospitalize for a fall in the last 3 months? 2) Did your patient lose weight or did he loose the appetite? 3) Has your patient difficulties to see or listen? 4) Does your patient need help in the everyday life? 5) Has your patient a change of the cognitive functions? 6) Does your patient need a geriatric evaluation for one or several any reason that those cited previously? During a prospective observational study, a doctor non-geriatrician practitioner informed the GWT during a consultation of vascular medicine.

[Modalities of hospitalization in emergency of institutionalized patients].

Background And Aim: Institutionalized people represent 9 to 37% of the patients hospitalized in emergency. The aim of this study is to clarify practical conditions of decision and realization of an hospitalization in emergency from an institution.

Patients And Method: This is a prospective and descriptive longitudinal study of the hospitalizations in emergency of institutionalized elderly during six months, from 11 nursing homes.

Treatment of motor dysfunction in Parkinson's disease: an overview.

Levodopa remains the most effective treatment for Parkinson's disease (PD). However, the use of this drug is complicated by several adverse effects, in particular motor fluctuations and dyskinesias. Drugs providing more continuous dopaminergic stimulation and surgical approaches, such as deep-brain stimulation, have an important ameliorative effect on these problems.

Memantine enhances autonomy in moderate to severe Alzheimer's disease.

Background: Alzheimer's disease (AD) is the leading cause of dementia and its course renders patients functionally disabled. Memantine is the first drug to demonstrate a clinical benefit in the treatment of patients with moderately-severe to severe AD.

Objectives: Our objective was to illustrate the benefits of memantine on functional disability.