New triterpenoid saponin from the aerial part of Welw ex. Bak. (Fabaceae) and their antibacterial activities.

The chemical investigation of the aerial part of led to isolation of a new triterpenoid glycoside named Canescensoside () and four known compounds including longispinogenin-3---D-glucuronopyranoside (), -sitosterol-3---D-glucoside (), apigenin-7---D-glucopyranoside () and apigenin-7--[-L-rhamnopyranosyl-(1→3)--D-glucopyranoside] (). Structures of compounds were assigned by interpretation of their spectral data, mainly 1D and 2D NMR, HRESIMS, and by comparison with the reported data. The MeOH extract, EtOAc and -BuOH fractions as well as isolated compounds were tested for their antibacterial activities against four bacteria strains among which, two Gram-negative ( ATCC 76110 and ATCC 8739) and two Gram-positive ( ATCC 29212 and ATCC 25923) bacteria using the broth microdilution method.

Complex secondary metabolites from Ludwigia leptocarpa with potent antibacterial and antioxidant activities.

Diarrhea continues to be one of the most common causes of morbidity and mortality among infants and children in developing countries. The aim of the present study was to evaluate the antibacterial and antioxidant activities of extracts and compounds from Ludwigia leptocarpa, a plant traditionally used for its vermifugal, anti-dysenteric, and antimicrobial properties. A methanol extract was prepared by maceration of the dried plant and this was successively extracted with ethyl acetate to obtain an EtOAc extract and with n-butanol to obtain an n-BuOH extract.

Owariensisone: a new iridolactone from the whole plant of Brillantaisia owariensis P. Beauv.

From the whole plant of Brillantaisia owariensis P. Beauv, a new iridolactone, owariensisone (1) together with six known compounds (nepetin-7-O-glucoside, choline, sucrose, mannitol, xylitol, 1-O-palmitoyl-2-eicosanoyl-3-O-(6-amino-6-deoxy)-β-d-glucopyranosyl-glycerol) were isolated. Structures of these compounds were established by direct interpretation of their spectral data, mainly HR-TOFESIMS, 1-D NMR ((1)H and (13)C) and 2-D NMR ((1)H-(1)H COSY, HSQC, HMBC, NOESY, TOCSY and DOCSY) and by comparison with the literature.

Leptocarposide: a new triterpenoid glycoside from Ludwigia leptocarpa (Onagraceae).

A new triterpenoid bidesmoside (leptocarposide) possessing an acyl group in their glycosidic moiety (1), together with the known luteolin-8-C-glucoside (2) and 1-O-β-D-glucopyranosyl-(2S,3R,8E)-2-[(2'R)-2-hydroxypalmitoylamino]-8-octadecen-1,3-diol (3) was isolated from the n-butanol-soluble fraction of whole plant of Ludwigia leptocarpa (Nutt) Hara (Onagraceae). Structure of compound 1 has been assigned on the basis of spectroscopic data ((1)H and (13)C NMR, (1)H-(1)H COSY, HSQC, HMBC, and ROESY), mass spectrometry, and by comparison with the literature. This compound was further screened for its potential antioxidant properties by using the radical scavenging assay model 2,2-diphenyl-1-picrylhydrazyl and reveals non-potent antioxidant activities, while compound 2 shows SC50 of 0,038 mM.