Publications by authors named "Florence Blanc-Jouvan"

Background: Although heritability of venous thromboembolism (VTE) is high, the thrombophilia screening appears to be positive only in a minority of VTE patients. Adding rare variants screening to identify VTE missing heritability still requires further assessment.

Objective: We report the results of a panel strategy after 3 years of application.

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Article Synopsis
  • Bleeding risk assessment before surgery in patients with rare inherited bleeding disorders is complex, despite established bleeding scores and clotting factor measurements.
  • A study involving 178 patients with low coagulation levels analyzed how hemostasis experts managed bleeding risks during 207 surgical procedures and the resulting bleeding outcomes.
  • Results showed that most surgeries were performed without factor replacement, particularly in mild deficiencies, and indicated that factor levels and the type of surgery are more critical for deciding perioperative treatment than bleeding scores.
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We report a case of a 62-year-old man who developed cerebral venous sinus thrombosis with subarachnoid hemorrhage and concomitant thrombocytopenia, which occurred 13 days after ChAdOx1 nCov-19 injection. The patient died in the intensive care unit after heparin infusion and platelet transfusion. The key clinical purpose of this case report is to better understand how to confirm vaccine-induced immune thrombotic thrombocytopenia VITT).

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