Publications by authors named "Florence Anne Richard"

Article Synopsis
  • Alpha satellite DNA is a major feature of primate centromeres, showing considerable sequence diversity and organization, studied primarily in great apes prior to this research.
  • This study utilizes high throughput sequencing to analyze two Old World monkey species, revealing two main monomer families (C1 and C2) and numerous specific subfamilies that indicate distinct evolutionary pathways.
  • Findings highlight dynamic changes in alpha satellite DNA, including the emergence of new variants and interchromosomal transfers, along with evidence of selective amplification and distribution influenced by specific genomic mechanisms.
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Background: Alpha satellite is the major repeated DNA element of primate centromeres. Evolution of these tandemly repeated sequences has led to the existence of numerous families of monomers exhibiting specific organizational patterns. The limited amount of information available in non-human primates is a restriction to the understanding of the evolutionary dynamics of alpha satellite DNA.

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The karyotypes of 28 specimens belonging to 26 species of Cercopithecinae have been compared with each other and with human karyotype by chromosome banding and, for some of them, by Zoo-FISH (human painting probes) techniques. The study includes the first description of the karyotypes of four species and a synonym of Cercopithecus nictitans. The chromosomal homologies obtained provide us with new data on a large number of rearrangements.

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