Publications by authors named "Flora R Sapp"
Article Synopsis
- This review highlights recent studies on how dietary changes and nutritional interventions impact the human microbiome across various regions, emphasizing benefits of fiber-rich foods in preventing diseases.
- It shows that disruptions to the microbiome in impoverished areas can lead to chronic malnutrition and underlines the critical role of breastfeeding.
- The findings reveal significant shifts in microbial composition and metabolic products with dietary changes, but point out the need for further research to measure their health benefits more accurately.
Am J Clin Nutr
February 2020
Article Synopsis
- - Alaska Native (AN) people have the highest known rate of colorectal cancer (CRC) globally, while rural Africans (RA) have the lowest, suggesting that dietary differences may influence CRC risk through their effect on gut microbiota.
- - A study compared the dietary habits and gut microbiota of healthy middle-aged volunteers from AN and RA, revealing that AN participants had higher fat and animal protein intake, lower fiber, and a distinct microbial composition linked to tumor-promoting metabolites.
- - Results showed that AN individuals had adenomatous polyps and lower butyrate levels, a tumor-suppressive metabolite, alongside higher levels of deoxycholic acid, a tumor-promoting substance; thus, the differing metabolite profiles
