Publications by authors named "Flora Lum"
Article Synopsis
- The study aimed to analyze the treatment patterns and outcomes of pneumatic retinopexy (PnR) in patients with rhegmatogenous retinal detachments (RRD) utilizing data from the IRIS® Registry over the years 2013-2022.
- Results showed that the overall single-operation success (SOS) rate for PnR was 59.82%, with specific complications noted, such as vitreous hemorrhage in 9.1% of cases, and poorer visual acuity outcomes for eyes that failed the procedure.
- The findings concluded that, while PnR is widely used, its SOS rate is lower than previously reported, and phakic eyes had better outcomes compared to pseud
Purpose: To determine the nationwide prevalence and geographic distribution of idiopathic intracranial hypertension (IIH) among women in the United States.
Design: Retrospective cross-sectional study using Medicaid claims and electronic health record data from the IRIS® Registry (Intelligent Research in Sight) and Sight Outcomes Research Collaborative (SOURCE).
Participants: Female Medicaid beneficiaries 18 to 55 years of age with IIH diagnoses and prescriptions for acetazolamide or methazolamide in 2018 were identified, excluding those with other causes of intracranial hypertension.
This retrospective cohort study describes the real-world incidence and maintenance of clinically meaningful intraocular pressure (IOP) reduction ("response") following stand-alone phacoemulsification for 667,987 eyes with suspected or confirmed glaucoma in the IRIS Registry (Intelligent Research in Sight) from 1/1/2013-9/30/2019. Intraocular pressure responders had ≥ 20% IOP reduction in daily mean IOP from baseline on two consecutive postoperative visits. We declared failure if a responder no longer maintained ≥ 20% IOP reduction.
View Article and Find Full Text PDFPurpose: To describe the prevalence of missing sociodemographic data in the IRIS® (Intelligent Research in Sight) Registry and to identify practice-level characteristics associated with missing sociodemographic data.
Design: Cross-sectional study.
Participants: All patients with clinical encounters at practices participating in the IRIS Registry prior to December 31, 2020.
Minimally invasive glaucoma surgery (MIGS) refers to a group of procedures generally characterized by an ab interno approach, minimal trauma to ocular tissue, moderate efficacy, an excellent safety profile, and rapid recovery. The number of MIGS procedures continues to increase, and their use has become widespread among glaucoma and cataract specialists. Standardization of the methodology and reporting of clinical endpoints in MIGS investigations enhances interpretation and comparison across different studies.
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- The study analyzed the rate of loss to follow up (LTFU) among patients with proliferative diabetic retinopathy (PDR) in the U.S. who underwent anti-VEGF therapy and/or panretinal photocoagulation (PRP) from 2013 to 2018.
- 11.7% of eyes treated for PDR were found to be LTFU, with varying rates for different treatment types: 12.3% for anti-VEGF, 12.6% for PRP, and 10.8% for combined treatments.
- Risk factors for LTFU included minority racial/ethnic backgrounds, unilateral disease, and worse baseline vision, while patients with
Purpose: To link compliant, universal Digital Imaging and Communications in Medicine (DICOM) ophthalmic imaging data at the individual patient level with the American Academy of Ophthalmology IRIS Registry (Intelligent Research in Sight).
Design: A retrospective study using de-identified EHR registry data.
Subjects Participants Controls: IRIS Registry records.
Purpose: To evaluate risk factors for intraocular pressure (IOP) spike after cataract surgery using the IRIS® Registry (Intelligent Research in Sight).
Design: Retrospective clinical cohort study.
Participants: Adults with IRIS Registry data who underwent stand-alone phacoemulsification from January 1, 2013, through September 30, 2019.
Shifts in ophthalmic care utilization during the COVID-19 pandemic in the US.
Commun Med (Lond)
December 2023
Background: Healthcare restrictions during the COVID-19 pandemic, particularly in ophthalmology, led to a differential underutilization of care. An analytic approach is needed to characterize pandemic health services usage across many conditions.
Methods: A common analytical framework identified pandemic care utilization patterns across 261 ophthalmic diagnoses.
Purpose: To assess the prevalence and risk factors of blindness among patients newly diagnosed with primary angle closure glaucoma (PACG) in the United States.
Design: Retrospective cross-sectional study.
Methods: Eligible patients from the American Academy of Ophthalmology (AAO) Intelligent Research in Sight (IRIS) Registry had newly diagnosed PACG, defined as: 1) observable during a 24-month lookback period from index date of PACG diagnosis; 2) no history of eye drops, laser, or cataract surgery unless preceded by a diagnosis of anatomical narrow angle (ANA); and 3) no history of glaucoma surgery.
Unlabelled: The rapid progress of large language models (LLMs) driving generative artificial intelligence applications heralds the potential of opportunities in health care. We conducted a review up to April 2023 on Google Scholar, Embase, MEDLINE, and Scopus using the following terms: "large language models," "generative artificial intelligence," "ophthalmology," "ChatGPT," and "eye," based on relevance to this review. From a clinical viewpoint specific to ophthalmologists, we explore from the different stakeholders' perspectives-including patients, physicians, and policymakers-the potential LLM applications in education, research, and clinical domains specific to ophthalmology.
View Article and Find Full Text PDFPurpose: To assess risk factors for worse visual acuity (VA) outcomes after intraocular lens (IOL) exchange, and the most common postsurgical complications.
Design: Retrospective cohort study.
Participants: Eyes from patients 18 years of age and older in the IRIS® Registry (Intelligent Research in Sight) that underwent IOL exchange in the United States between 2013 and 2019.
The impact of month and season on the incidence of giant cell arteritis: an Intelligent Research in Sight (IRIS) Registry analysis.
Graefes Arch Clin Exp Ophthalmol
February 2024
Purpose: Previous investigations into the relationship between season and the incidence of giant cell arteritis (GCA) have produced conflicting results. This study aimed to explore the impact of season and new diagnoses of GCA in a more definitive sense by employing the large dataset of the Intelligent Research in Sight (IRIS) database.
Methods: The IRIS Registry was queried to identify new cases of GCA from 2013 to 2021.