A new case series on etanercept treatment for toxic epidermal necrolysis.

Background: Toxic epidermal necrolysis (TEN) is a severe, potentially lethal drug reaction for which no standard treatment is available.

Objective: To describe 17 consecutive TEN patients treated with a single dose of etanercept, a TNF-alpha inhibitor.

Materials & Methods: Comorbidities and any drug treatment initiated within the previous month were recorded on admission.

Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects.

Intradermal therapy, known as mesotherapy, is a technique used to inject a drug into the surface layer of the skin. In particular, it involves the use of a short needle to deposit the drug in the dermis. The intradermal microdeposit modulates the drug's kinetics, slowing absorption and prolonging the local mechanism of action.

Toxic epidermal necrolysis successfully treated with etanercept.

Toxic epidermal necrolysis (TEN) is a rare and acute severe adverse reaction to drugs, characterised by massive apoptosis and widespread epidermal and mucosal detachment. Although no gold standard therapy exists, human i.v.