Background: Rheopheresis is a double-filtration plasmapheresis that removes high-molecular-weight molecules from the plasma and thereby lowers blood viscosity. This treatment has been proposed in hemodialysis (HD) patients for chronic limb-threatening ischemia (CLTI), but very few studies have evaluated the usefulness of this technique.
Principal Objective: To assess 1-year amputation-free survival (AFS) of HD patients suffering from CLTI treated by rheopheresis.