Effect of metronidazole ophthalmic solution on corneal neovascularization in a rat model.

Purpose: To evaluate the effect of metronidazole ophthalmic solutions on corneal neovascularization (CNV) in a rat model.

Methods: A chemical burn was created in the right central cornea of 40 rats. Animals were randomized and distributed into four study groups (n = 10 rats per group) designated Met_0.

Corneal angiogenesis based on different protocols of alkaline cauterization in murine models.

Purpose:: To establish and compare protocols of alkaline cauterization for inducing corneal angiogenesis in murine models.

Methods:: Twenty-four adult Wistar rats were distributed into four groups (G1, G2, G3, and G4). The right eye cornea from each rat was cauterized using filter paper (3 mm), soaked in a solution of silver and potassium nitrates (3:1).