Publications by authors named "Flint M Beal"
Article Synopsis
- * Scientists created transgenic mice with a specific mutation (hPFN1G118V) to study how it impacts motor neuron disease, revealing significant similarities to human ALS symptoms including neuron loss and muscle atrophy.
- * The study suggests that the mutant profilin1 disrupts actin dynamics, leading to severe damage in certain neurons, and these mutant mice could serve as a valuable model for understanding ALS mechanisms.
Genetic inactivation of the mitochondrial self-destruction mechanism improves cognition in a mouse model of Alzheimer’s disease (pages 1097–1105).
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