Publications by authors named "Fleur Boel"

Objective: Small studies in athletes showed that primary cam morphology (PCM) gradually develops during skeletal growth. However, the prevalence of PCM in early adolescents is poorly understood. We aimed to estimate the overall and birth-assigned sex-specific prevalence of PCM in early adolescents from the general population.

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Objective: To study the association between various radiographic definitions of acetabular dysplasia (AD) and incident radiographic hip osteoarthritis (RHOA), and to analyze in subgroups.

Methods: Hips free of RHOA at baseline and with follow-up within 4-8 years were drawn from the World COACH consortium. The Wiberg center edge angle (WCEA), acetabular depth width ratio (ADR), and the modified acetabular index (mAI) were calculated.

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Objectives: To determine the association between baseline cam morphology and self-reported hip pain assessed at annual visits over a 10-year follow-up period stratified by biological sex. The secondary aim was to study the association between the magnitude of cam morphology and the severity of pain in symptomatic hips.

Methods: The nationwide prospective Cohort Hip and Cohort Knee (CHECK) study includes 1,002 participants aged 45-65 years.

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Article Synopsis
  • The study aimed to explore different subtypes of cam morphology on hip radiographs and their link to developing radiographic hip osteoarthritis (RHOA) over ten years.
  • The CHECK study included over 1,000 participants aged 45-65, analyzing the relationship between specific cam morphology shapes and the onset of RHOA, with results indicating varying risk factors based on sex.
  • Four distinctive cam morphology subtypes were identified, with only certain subtypes acting as risk factors for RHOA, suggesting that cam morphology should be analyzed beyond just the alpha angle measurement.
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Purpose: Hip osteoarthritis (OA) is a major cause of pain and disability worldwide. Lack of effective therapies may reflect poor knowledge on its aetiology and risk factors, and result in the management of end-stage hip OA with costly joint replacement. The Worldwide Collaboration on OsteoArthritis prediCtion for the Hip (World COACH) consortium was established to pool and harmonise individual participant data from prospective cohort studies.

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Objective: The objective of this study was to assess the relationship between pincer morphology and radiographic hip osteoarthritis (RHOA) over 2, 5, 8, and 10 years' follow-up and to study the interaction between pincer morphology and pain.

Methods: Individuals from the prospective Cohort Hip and Cohort Knee study were drawn. Anteroposterior pelvic and false profile radiographs were obtained.

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Objective: To determine the association between cam morphology and the development of radiographic hip osteoarthritis (RHOA) at four time points within 10-year follow-up.

Design: The nationwide prospective Cohort Hip and Cohort Knee study includes 1002 participants aged 45-65 years with 2-, 5-, 8-, and 10-year follow-ups. The associations of cam morphology (alpha angle >60°) and large cam morphology (alpha angle >78°) in hips free of osteoarthritis at baseline (Kellgren & Lawrence (KL) grade <2) with the development of both incident RHOA (KL grade≥2) and end-stage RHOA (KL grade≥3) were estimated using logistic regression with generalized estimating equation at each follow-up and using Cox regression over 10 years, adjusted for age, sex, and body mass index.

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Article Synopsis
  • Acetabular dysplasia is a leading cause of hip osteoarthritis and surgery, and can develop in childhood, not just infancy.
  • This systematic review examines the prevalence of acetabular dysplasia in healthy children aged 2-18 by analyzing various studies and assessing their quality.
  • Findings show that the prevalence of mild dysplasia ranges from 13.4% to 25.6% and severe dysplasia from 2.2% to 10.9%, highlighting the condition's commonality beyond infancy.
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Introduction: To minimize the risk of local tumor progression after thermal ablation of liver malignancies, complete tumor ablation with sufficient ablation margins is a prerequisite. This has resulted in ablation margin quantification to become a rapidly evolving field. The aim of this systematic review is to give an overview of the available literature with respect to clinical studies and technical aspects potentially influencing the interpretation and evaluation of ablation margins.

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