Prevention of air leakage by spraying vivostat fibrin sealant after lung resection in pigs.

Study Objectives: To evaluate Vivostat fibrin sealant in the prevention of air leakage after experimental lung resection in pigs.

Design: Randomized study.

Setting: University laboratory.

Comparative kinetics of polymerisation of three fibrin sealants and influence on timing of tissue adhesion.

The clinical performance of fibrin sealants may be influenced by physical properties such as elasticity, tensile strength, and ability to adhere to human tissue. These properties are related to the internal structure of the fibrin sealant that builds as it polymerises. Analysis of the minimum polymerisation time to achieve a functional fibrin clot is clinically important.