How and why do health system factors influence general dentists' participation in publicly funded, contracted primary dental care services: A realist review.

Objectives: To identify health system contexts and mechanisms influencing general dental practitioners' (GDPs) participation in state funded, contracted primary oral healthcare.

Methods: Peer-reviewed articles and other sources were identified via EMBASE, Medline (OVID), Web of Science and Google Scholar databases, grey literature search, citation tracking and expert recommendations. Studies meeting the inclusion criteria were assessed for rigour, relevance and richness, and coded to identify data relating to contexts, mechanisms and outcomes.

Reciprocal and non-reciprocal effects of clinically relevant SETBP1 protein dosage changes.

Many genes in the human genome encode proteins that are dosage sensitive, meaning they require protein levels within a narrow range to properly execute function. To investigate if clinically relevant variation in protein levels impacts the same downstream pathways in human disease, we generated cell models of two SETBP1 syndromes: Schinzel-Giedion Syndrome (SGS) and SETBP1 haploinsufficiency disease (SHD), where SGS is caused by too much protein, and SHD is caused by not enough SETBP1. Using patient and sex-matched healthy first-degree relatives from both SGS and SHD SETBP1 cases, we assessed how SETBP1 protein dosage affects downstream pathways in human forebrain progenitor cells.

Large-scale and long-term wildlife research and monitoring using camera traps: a continental synthesis.

Camera traps are widely used in wildlife research and monitoring, so it is imperative to understand their strengths, limitations, and potential for increasing impact. We investigated a decade of use of wildlife cameras (2012-2022) with a case study on Australian terrestrial vertebrates using a multifaceted approach. We (i) synthesised information from a literature review; (ii) conducted an online questionnaire of 132 professionals; (iii) hosted an in-person workshop of 28 leading experts representing academia, non-governmental organisations (NGOs), and government; and (iv) mapped camera trap usage based on all sources.

Anti-microbial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase.

Cetylpyridinium chloride (CPC) is a quaternary ammonium antimicrobial used in numerous personal care products, human food, cosmetic products, and cleaning solutions. Yet, there is minimal published data on CPC effects on eukaryotes, immune signaling, and human health. Previously, it was shown that low-micromolar CPC inhibits rat mast cell function by inhibiting antigen (Ag)-stimulated Ca mobilization, microtubule polymerization, and degranulation.

The effect of haemoglobin and blood transfusion on preterm infant gut perfusion and injury.

Introduction: There is significant uncertainty regarding the role that anaemia or red blood cell transfusion (RBCT) plays in the development of gut injury in preterm infants. This study evaluated Near Infrared Spectroscopy (NIRS) together with a range of known biomarkers of gut inflammation to identify their relationship with anaemia and RBCT.

Method: A prospective observational study of preterm infants born at <30 weeks gestation was conducted from birth until either 36 weeks post conceptional age or discharge home.

A Cross-Sectional Evaluation of the Association between Orthodontic Treatment, Retention Modality and the Prevalence of Gingival Recession.

Purpose: The prevalence of gingival recession in orthodontically treated patients and the relative impact of retainer type on its occurrence remain poorly understood. The objective of this study was to investigate the association between previous orthodontic treatment and retainer type on the long-term prevalence of gingival recession and to evaluate the role of other patient-related factors, such as gender, age, smoking and gingival phenotype.

Materials And Methods: We included subjects both with and without a history of previous orthodontics (at least 5 years post-treatment).

Indexing status of orthodontic research published in presumed predatory journals: A bibliometric study.

Objectives: To examine the indexing status of presumed predatory orthodontic publications within established scientific databases.

Methods: Six electronic databases were searched to identify English language orthodontic articles published in 2022. Equal numbers of articles from legitimate (n = 159) and suspect or predatory journals (n = 159) were considered.

School-based organizational skills training for students in grades 3-5: A cluster randomized trial.

Objective: Research has demonstrated the effectiveness of interventions to reduce organizational skills deficits and homework problems, including the clinic-based Organizational Skills Training (OST-C) program (Abikoff et al., 2013). In this study, OST-C was adapted for schools as a small-group (Tier 2) intervention delivered by school partners (OST-T2).

Directly printed aligner therapy: A 12-month evaluation of application and effectiveness.

Introduction: Directly printed aligners (DPAs) are gaining in popularity, potentially streamlining manufacturing, decreasing environmental waste, and offering enhanced adaptation and tailoring. This transition has been facilitated by advances in materials, software, and production. Although DPAs may have enhanced versatility and application in the management of more complex malocclusions, there is little research evaluating their effectiveness.

The role of orthodontics in the prevention and management of gingival recession.

Careful management of orthodontic patients presenting with thin periodontal phenotype is paramount. Combined orthodontic-periodontal input is helpful both in terms of diagnosis and stabilisation but also to coordinate care. Well-executed orthodontics offers the potential to safeguard periodontal health but also to induce significant aesthetic improvement either in isolation or combined with increasingly predictable muco-gingival procedures.

Periodontitis: orthodontic implications and management.

Orthodontics is increasingly ingrained in the overall management of patients with periodontitis. Advanced periodontitis is often characterised by pathological tooth migration, loss of posterior support and incisal proclination. Orthodontics may therefore offer both aesthetic and therapeutic benefit.

Is orthodontic research falling prey to obscure and predatory journals? A bibliometric study.

Aims: To evaluate where orthodontic research papers are published and to explore potential relationships between the journal of publication and the characteristics of the research study and authorship.

Methods: An online literature search of seven research databases was undertaken to identify orthodontic articles published in English language over a 12-month period (1 January-31 December 2022) (last search: 12 June 2023). Data extracted included journal, article, and author characteristics.

A systematic literature review of the impact of impaired self-awareness on the process of rehabilitation in acquired brain injury.

Background: Impaired self-awareness (ISA) is common in individuals with an acquired brain injury (ABI) and can lead to reduced awareness of one's difficulties. Previous reviews have found that ISA impacts on functional outcomes in rehabilitation. However, to date there has not been a systematic literature review which examines how ISA impacts on the process of rehabilitation in ABI populations.

Examining the impact and response to an outbreak of carbapenemase-producing in a neonatal unit in the United Kingdom: An outbreak report.

Background: Carbapenemase-producing (CPE) are a group of Gram-negative bacteria causing global concern due to their resistance to carbapenems. In this report, we detail the learning points from a CPE outbreak in a tertiary neonatal unit (NU) in the UK.

Methods: Routine surveillance screening (rectal swabs) of babies on the NU identified a potential cluster of CPE carriage.

Antimicrobial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase.

Cetylpyridinium chloride (CPC) is a quaternary ammonium antimicrobial used in numerous personal care products, human food, cosmetic products, and cleaning solutions. Yet, there is minimal published data on CPC effects on eukaryotes, immune signaling, and human health. Previously, we showed that low-micromolar CPC inhibits rat mast cell function by inhibiting antigen (Ag)-stimulated Ca mobilization, microtubule polymerization, and degranulation.

The Michigan Farmworker Project: A Community-Based Participatory Approach to Research on Precarious Employment and Labor Exploitation of Farmworkers.

Precarious employment is an important social determinant of health inequities. Through in-depth qualitative interviews ( = 35), we examine precarious employment and labor exploitation, their potential impact on the working environment, and, ultimately, the health of farmworkers. We present results from the community-based participatory Michigan Farmworker Project.

A contact binary satellite of the asteroid (152830) Dinkinesh.

Asteroids with diameters less than about 5 km have complex histories because they are small enough for radiative torques (that is, YORP, short for the Yarkovsky-O'Keefe-Radzievskii-Paddack effect) to be a notable factor in their evolution. (152830) Dinkinesh is a small asteroid orbiting the Sun near the inner edge of the main asteroid belt with a heliocentric semimajor axis of 2.19 AU; its S-type spectrum is typical of bodies in this part of the main belt.