Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch.

Diabetes mellitus type 2 (DMT2) promotes Achilles tendon (AS) degeneration and exercise could modulate features of DMT2. Hence, this study investigated whether tenocytes of non DMT2 and DMT2 rats respond differently to normo- (NG) and hyperglycemic (HG) conditions in the presence of tumor necrosis factor (TNF)α or cyclic stretch. AS tenocytes, isolated from DMT2 (fa/fa) or non DMT2 (lean, fa/+) adult Zucker Diabetic Fatty (ZDF) rats, were treated with 10 ng/mL TNFα either under NG or HG conditions (1 g/L vs.

Flow field data of three-dimensional Riemann problems.

Common validation and verification test cases for compressible flow solvers are only one- or two-dimensional. Such flows, however, are inherently three-dimensional. The provided data contains simulation results of genuine three-dimensional Riemann problems computed with the open-source compressible flow solver ALPACA.

Urethral Bulking.

Objective: This Clinical Practice Statement aims to provide clinicians with evidence-based guidance for the use of urethral bulking agents (UBAs) in the treatment of stress urinary incontinence (SUI).

Methods: We conducted a structured search of the English literature published from January 1960 to November 2022. Search terms identified studies of both current and historic UBAs.

[Hearing in the elderly: Employees' perspectives on hearing care in long-term care facilities. A qualitative study].

Hearing in the elderly: Employees' perspectives on hearing care in long-term care facilities. A qualitative study Hearing impairment is common among the elderly. More than half of individuals 80 years and older exhibit severe hearing loss, and few retain good hearing performance.

Reconstruction of Urethral Sphincter With Polyacrylamide Hydrogel.

Importance: Urethral bulking is an alternative to synthetic midurethral sling for the treatment of stress urinary incontinence (SUI) in women. Urethral bulking agents, which are injected in the submucosal tissues of the proximal urethra/bladder neck, have demonstrated less adverse effects with similar satisfaction rates but lower subjective and objective cure rates when compared with midurethral sling. Cystoscopic Reconstruction of External Sphincter Technique (CREST) is a novel technique, which reinforces the natural closure mechanism of the external urinary sphincter (EUS).

Implementation, mechanisms of change and contextual factors of a complex intervention to improve interprofessional collaboration and the quality of medical care for nursing home residents: study protocol of the process evaluation of the interprof ACT intervention package.

Background: To improve interprofessional collaboration between registered nurses (RNs) and general practitioners (GPs) for nursing home residents (NHRs), the interprof ACT intervention package was developed. This complex intervention includes six components (e.g.

Measuring care coordination in German primary care - adaptation and psychometric properties of the Medical Home Care Coordination Survey.

Background: Continuity of care is associated with many benefits for patients and health care systems. Therefore measuring care coordination - the deliberate organization of patient care activities between two or more participants - is especially needed to identify entries for improvement. The aim of this study was the translation and cultural adaptation of the Medical Home Care Coordination Survey (MHCCS) into German, and the examination of the psychometric properties of the resulting German versions of the MHCCS-P (patient version) and MHCCS-H (healthcare team version).

Effects of strategies to improve general practitioner-nurse collaboration and communication in regard to hospital admissions of nursing home residents (interprof ACT): study protocol for a cluster randomised controlled trial.

Background: In Germany, up to 50% of nursing home residents are admitted to a hospital at least once a year. It is often unclear whether this is beneficial or even harmful. Successful interprofessional collaboration and communication involving general practitioners (GPs) and nurses may improve medical care of nursing home residents.

Reducing antibiotic use for uncomplicated urinary tract infection in general practice by treatment with uva-ursi (REGATTA) - a double-blind, randomized, controlled comparative effectiveness trial.

Background: Uncomplicated urinary tract infections (UTI) are common in general practice and usually treated with antibiotics. This contributes to increasing resistance rates of uropathogenic bacteria. A previous trial showed a reduction of antibiotic use in women with UTI by initial symptomatic treatment with ibuprofen.

Interprofessional collaboration in nursing homes (interprof): development and piloting of measures to improve interprofessional collaboration and communication: a qualitative multicentre study.

Background: Given both the increase of nursing home residents forecast and challenges of current interprofessional interactions, we developed and tested measures to improve collaboration and communication between nurses and general practitioners (GPs) in this setting. Our multicentre study has been funded by the German Federal Ministry of Education and Research (FK 01GY1124).

Methods: The measures were developed iteratively in a continuous process, which is the focus of this article.

Interprofessional collaboration in nursing homes (interprof): a grounded theory study of general practitioner experiences and strategies to perform nursing home visits.

Background: Interprofessionalism, considered as collaboration between medical professionals, has gained prominence over recent decades and evidence for its impact has grown. The steadily increasing number of residents in nursing homes will challenge medical care and the interaction across professions, especially nurses and general practitioners (GPs). The nursing home visit, a key element of medical care, has been underrepresented in research.

Interprofessional collaboration and communication in nursing homes: a qualitative exploration of problems in medical care for nursing home residents – study protocol.

Aim: This study explores the current state of collaboration and communication between nurses and general practitioners in nursing homes, as well as needs and expectations of nursing home residents and their families. Finally, we aim to develop a new model of collaboration and communication.

Background: Rising numbers of residents in nursing homes present a challenge for general practice and nursing in most Western countries.

Gross and microscopic hematuria: guidelines for obstetricians and gynecologists.

Although gross hematuria is a relatively uncommon condition in general obstetrics and gynecology practice, microscopic hematuria is a common incidental finding during routine antepartum or gynecologic office visits. The proper evaluation and treatment options are understudied in females. In fact, work-up of females is controversial, and no consensus guidelines exist at this time.

Intelligent monitoring networks--transformation of data into information for water management.

The EU-WFD requires certain monitoring tasks, which yet cannot be fulfilled by automated monitoring devices. Nevertheless, the technical progress of recent years allows monitoring station designs, which enable long-term field application under reasonable maintenance demand. State-of-the-art monitoring stations allow the setup and operation of intelligent monitoring networks, which deliver quality proved and utilisable information to the end-user as opposed to a collection of time-series.

Investigative monitoring in the context of detecting anthropogenic impact on an epipotamal river.

In the context of an investigative monitoring programme a monitoring system comprising of a water quality monitoring station and a camera station has been installed and operated for more than one year. The monitoring target was to investigate changes of water quality which can be related to a repeated occurrence of foam, observed at a river stretch downstream the monitoring station. The extent and frequency of foam buildup was recorded by means of the camera station.

Correlation of abdominal leak point pressure with objective incontinence severity in men with post-radical prostatectomy stress incontinence.

Aims: To determine if the abdominal leak point pressure (ALPP) correlates with objective incontinence severity in patients suffering from post-prostatectomy stress incontinence.

Methods: Twenty-nine men were evaluated for urinary incontinence after radical prostatectomy with videourodynamics and a 24-hr pad test. ALPP was determined with and without a 7-French urodynamics catheter and the lowest value was accepted.

Spectral in-situ analysis of NO2, NO3, COD, DOC and TSS in the effluent of a WWTP.

An in-situ UV spectrometer was applied to the effluent of a WWTP in Switzerland and calibrated using a multivariate calibration algorithm based on PLS regression. Except for nitrite, the calibration was based on comparative measurements of the effluent in the plant laboratory. Samples made of stock solution added to three different matrices prepared in the EAWAG laboratory were used for the nitrite calibration because the effluent concentrations were always in the range of 0.

Time-resolved delta spectrometry: a method to define alarm parameters from spectral data.

Alarm parameters are in many ways different from measurements of well defined chemical substances. Being confronted with an increasing number of potentially harmful compounds as well as financial and logistic constraints, new variables (such as alarm parameters) that allow for an integrated assessment or for a first screening can be a solution. To monitor for surrogate or aggregate variables can be a useful strategy to overcome some of the constraints.

On-line monitoring for control of a pilot-scale sequencing batch reactor using a submersible UV/VIS spectrometer.

A submersible UV/VIS spectrometer was used to monitor a pilot-scale sequencing batch reactor (SBR). The instrument utilises the whole UV/VIS range between 200 and 750 nm. With just one single instrument nitrate, organic matter and suspended solids can be measured simultaneously.

Pelvic floor reconstruction: state-of-the-art and beyond.

Reconstructive surgery for pelvic-floor dysfunction is challenging and complex. It requires an extensive familiarity with pelvic anatomy and a wide armamentarium of surgical procedures to offer patients with various structural defects. Not every patient is suited for every procedure and the surgeon must be able to individualize the approach.

Monitoring of a paper mill wastewater treatment plant using UV/VIS spectroscopy.

A submersible UV/VIS spectrometer was used to monitor a paper mill wastewater treatment plant. It utilises the UV/VIS range (200-750 nm) for simultaneous measurement of COD, filtered COD, TSS and nitrate with just a single instrument. The instrument measures in-situ, directly in the process.

In situ sensing of volatile organic compounds in groundwater: first field tests of a mid-infrared fiber-optic sensing system.

A prototype mid-infrared sensor system for the determination of volatile organic pollutants in groundwater was developed and tested under real-world conditions. The sensor comprises a portable Fourier transform infrared spectrometer, coupled to the sensor head via mid-infrared transparent silver halide fiber-optic cables. A 10 cm unclad middle section of the 6-m-long fiber is coated with ethylene propylene copolymer in order to enrich the analytes within the penetration depth of the evanescent field protruding from the fiber sensor head.