Publications by authors named "Fleck Margaux"
Article Synopsis
- - The study aimed to evaluate the effectiveness of patch tests (PTs) in identifying drugs causing non-immediate cutaneous adverse drug reactions (NICADRs) by comparing readings at days 3 (D3) and 4 (D4).
- - Findings revealed that only 13.7% of patients tested positive on D3, while 24.9% tested positive on D4, highlighting a significant increase in sensitivity with the later reading (p < 0.0001).
- - The research concluded that an additional reading at D4 improves the detection of culprit drugs in NICADRs, suggesting further investigations to confirm these results and explore the cost-effectiveness of this testing approach.
Background: Patch tests (PTs) with two readings have been used for decades to identify the culprit drug in nonimmediate cutaneous adverse drug reactions (NICADRs), followed more recently by late reading of intradermal tests (IDTs). Some teams tend to perform PTs with only one reading before IDTs or even directly perform IDTs.
Objectives: To evaluate the relevance of a late PT reading on day 4 (D4) in NICADRs.