Appl Biochem Biotechnol
October 2023
Biosurfactants can replace fossil-driven surfactants with positive environmental impacts, owing to their low eco-toxicity and high biodegradability. However, their large-scale production and application are restricted by high production costs. Such costs can be reduced using renewable raw materials and facilitated downstream processing.
View Article and Find Full Text PDFLupanine is an alkaloid used in the pharma industry as a building block or precursor in the synthesis of sparteine and also explored for drug synthesis in the pharma industry as a chiral selector. This alkaloid is found in lupin bean processing wastewaters originated from the debittering process to make these beans edible. In this work, a computational chemistry approach was taken to design molecularly imprinted polymers (MIPs) selecting itaconic acid, a biobased building block, as a functional monomer that can provide higher affinities for lupanine.
View Article and Find Full Text PDFNeural tissue engineering strategies are paramount to create fully mature neurons, necessary for new therapeutic strategies for neurological diseases or the creation of reliable in vitro models. Scaffolds can provide physical support for these neurons and enable cues for enhancing neural cell differentiation, such as electrical current. Coaxial electrospinning fibers, designed to fulfill neural cell needs, bring together an electroconductive shell layer (PCL-PANI), able to mediate electrical stimulation of cells cultivated on fibers mesh surface, and a soft core layer (PGS), used to finetune fiber diameter (951 ± 465 nm) and mechanical properties (1.
View Article and Find Full Text PDFNeurodegenerative diseases compromise the quality of life of increasing numbers of the world's aging population. While diagnosis is possible no effective treatments are available. Strong efforts are needed to develop new therapeutic approaches, namely in the areas of tissue engineering and (DBS).
View Article and Find Full Text PDFAim: To evaluate, in vitro, the mini-implant surface changes and the release of ions after immersion in artificial saliva during follow-up of 60 and 120 days.
Materials And Methods: As for the surface features, examined in a scanning electron microscope (SEM), before and after immersion in artificial saliva, there was a rough and uneven surface, suggestive of corrosion areas for the two trademarks evaluated after 120 days of immersion. The extracts generated in artificial saliva analysis were submitted to energy dispersive spectroscopy to identify the solid corrosion products produced on the surfaces of miniscrews.