Publications by authors named "Flavia Quaranta-Leoni"
Article Synopsis
- The study aims to assess the characteristics of advanced ocular surface squamous neoplasia and eyelid tumors, as well as the effectiveness of post-operative high-dose-rate interventional radiotherapy in their management.
- Nineteen patients with advanced cancers underwent surgery followed by HDR-IRT, delivering a total of 49 Gy in 14 fractions, focusing on local disease control as the primary outcome along with survival and toxicity as secondary outcomes.
- Results showed local recurrences in some cases, particularly with conjunctival melanomas and squamous cell carcinoma, with a median overall survival of 56.3 months; however, treatment effectiveness varied, highlighting the need for larger multicenter studies.
Article Synopsis
- The study evaluates the long-term effectiveness of the Cutler-Beard two-stage technique for reconstructing large full-thickness upper eyelid defects after tumor excision in 24 patients from 2000 to 2021.
- The majority of patients had basal cell carcinoma, with a mean follow-up of about 53 months; 45.8% experienced complications like upper eyelid entropion, but most were satisfied with the functional and aesthetic outcomes.
- While other reconstruction techniques are often preferred, the Cutler-Beard flap is suitable for significant horizontal eyelid defects exceeding 15 mm in vertical size, though different approaches might be needed for highly malignant tumors.
Article Synopsis
- Two cases of orbital hidrocystoma are reported, highlighting clinical features and management strategies for an enlarging orbital mass.
- One patient was a 48-year-old man with a mass near the supraorbital area, and the other was a 70-year-old man with a lesion near the lacrimal gland; both diagnoses were confirmed as apocrine hidrocystomas through histopathology.
- Post-surgery, mild nerve sensation loss in the first patient resolved quickly, and no recurrences were observed in either case during follow-up; these findings suggest that apocrine hidrocystomas, though rare in the orbit, should be included in the differential diagnosis for similar cystic masses.
Anophthalmic socket syndrome determines functional deficits and facial deformities, and may lead to poor psychological outcomes. This review aims to comprehensively evaluate the features of the syndrome, based on literature review and authors' clinical and surgical experience. An electronic database (PubMed,MEDLINE and Google Scholar) search of all articles written in English and non-English language with abstract translated to English on anophthalmic socket syndrome was performed.
View Article and Find Full Text PDFPurpose: To identify a rationale for correct surgical treatment of proximal lacrimal obstructions.
Methods: Retrospective review of 775 consecutive patients (974 eyes) with proximal lacrimal obstructions, operated on with customized surgery by a senior surgeon (FMQL) from January 2003 to December 2018.
Results: In case of punctal stenosis, punctoplasty was as effective as punctal dilatation with monocanalicular or bicanalicular stent (p > 0.
Article Synopsis
- The study aims to assess how muscle atrophy in the levator muscle of patients with unilateral congenital ptosis varies with the patient's age at the time of surgery.
- Histological analysis of the levator muscle from 29 patients revealed that younger patients (2-4 years) experienced mild atrophy, while older patients (4.1-11 years) exhibited severe atrophy characterized by significant muscle fiber changes.
- The findings suggest that not only does muscle degeneration occur after surgery, but severity increases with the patient's age, indicating that delaying surgical intervention could lead to worse muscle atrophy.