Publications by authors named "Flavia Maciel de Moraes"
The virus responsible for COVID-19 is designated "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2), a highly transmissible and pathogenic coronavirus. Although people of all ages are susceptible to SARS-CoV-2 infection, clinical manifestations may vary with age. The response of neonates to SARS-CoV-2 infection or exposure differs from that of children and adults.
View Article and Find Full Text PDFInflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life.
Marcelo Gomes Granja Letícia Pires Alves Marina Leardini-Tristão Michelle Edelman Saul Letícia Coelho Bortoni Flávia Maciel de Moraes Bianca Portugal Tavares de Moraes
J Neuroinflammation
February 2021
Article Synopsis
- - The study investigates how maternal sepsis affects cytokine levels and synaptic proteins in the brains of offspring mice, indicating potential lasting impacts on brain development and behavior.
- - Pregnant mice were exposed to sepsis through a bacterium, and the resulting offspring were assessed for motor skills, behavior, and cognitive abilities at different developmental stages.
- - Findings show that maternal sepsis leads to an increase in inflammatory cytokines and a decrease in important synaptic proteins, resulting in motor disabilities and behavioral issues, such as learning and memory problems in the young and adult mice.