Publications by authors named "Flavia Leite-Lima"
Article Synopsis
- The study presents a cohort of 24 patients treated for conventional ameloblastoma, focusing on the outcomes after marginal or segmental resections over 21 years.
- Most patients were middle-aged females, with the mandible being the most affected site and a predominance of multilocular lesions.
- The results indicate a low recurrence rate (8.33%) following surgery, with patients monitored for an average of 79.25 months, suggesting that marginal/segmental resection is effective in managing this type of tumor.
Background: Unicystic ameloblastoma is an encapsulated odontogenic neoplasm with a single cyst cavity. The conservative or aggressive surgical approaches used to treat the tumor directly affect recurrence rates. However, there is a lack of a standard protocol that can guide its management.
View Article and Find Full Text PDFAging is not a matter of choice; it is our fate. The "time-dependent functional decline that affects most living organisms" is coupled with several alterations in cellular processes, such as cell senescence, epigenetic alterations, genomic instability, stem cell exhaustion, among others. Age-related morphological changes in dental follicles have been investigated for decades, mainly motivated by the fact that cysts and tumors may arise in association with unerupted and/or impacted teeth.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to explore the metabolic pathways involved in the changes in epithelial lining of odontogenic keratocysts after a surgical procedure called marsupialization, comparing tissue samples before and after the procedure as well as adjacent oral mucosa.
- Researchers analyzed 18 tissue samples using advanced metabolomics techniques to identify differences in cellular processes related to inflammation, oxidative stress, and cell differentiation.
- The findings suggest that the metabolic changes linked to marsupialization could help in understanding the condition better and may lead to the development of targeted therapies for treating odontogenic keratocysts.
A nodule in the temporomandibular joint area.
Oral Surg Oral Med Oral Pathol Oral Radiol
July 2020