Publications by authors named "Flavia Cristina da Silva Salles"
The genetic diversity of the dengue virus is characterized by four circulating serotypes, several genotypes, and an increasing number of existing lineages that may have differences in the potential to cause epidemics and disease severity. Accurate identification of the genetic variability of the virus is essential to identify lineages responsible for an epidemic and understanding the processes of virus spread and virulence. Here, we characterize, using portable nanopore genomic sequencing, different lineages of dengue virus 2 (DENV-2) detected in 22 serum samples from patients with and without dengue warning signs attended at Hospital de Base of São José do Rio Preto (SJRP) in 2019, during a DENV-2 outbreak.
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- Chikungunya virus (CHIKV) has spread across 51 countries in the Americas since its first detection in the Caribbean in 2013, with a notable outbreak in the Brazilian Amazon region, particularly in Boa Vista, Roraima state, from 2014 to 2018.
- Researchers identified 20 new genomes of the CHIKV-East-Central-South-America (ECSA) lineage, indicating that a major outbreak was likely caused by this lineage introduced from northeast Brazil, despite the earlier presence of the Asian genotype.
- The study suggests a significant infection rate in Roraima's population and emphasizes the importance of combining genomic sequencing and digital data to enhance public health surveillance and response to CHIKV