Publications by authors named "Fiza Saleem"
The COVID-19 pandemic has affected the global health system and economies largely. Therefore, knowledge about the clinical and laboratory profiles of patients with COVID-19 would help in the management and prognosis of the disease. The immunological and hematological indices have emerged as critical determinants for the severity of the disease and the prognosis; however, association with COVID-19 is clouded.
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- The study focuses on creating a chimeric protein by fusing interleukin 24 with a tumor-targeting peptide (P20) to improve cancer treatment efficacy.
- Bioinformatics tools were used to analyze the protein's structure, revealing it has a basic nature, is 175 amino acids long, and weighs 20 kDa, with high structural quality.
- Docking and simulation studies suggest that the fusion protein is stable, interacts well, and shows potential as a targeted therapy for cancer.
Enteric fever, a persistent public health challenge in developing regions, is exacerbated by suboptimal socioeconomic conditions, contaminated water and food sources, and insufficient sanitation. This study delves into the antimicrobial susceptibility of Salmonella Typhi, uncovering the genetic underpinnings of its resistance. Analyzing 897 suspected cases, we identified a significant prevalence of typhoid fever, predominantly in males (58.
View Article and Find Full Text PDFObjective: This study was conducted to determine changes in lipid metabolism and liver enzyme status among HBV-positive patients with liver cirrhosis.
Methods: A total of 300 HBV-positive patients with liver cirrhosis and 200 healthy controls were included in this case-control study. The patients were recruited from several tertiary care hospitals in Lahore from March to October 2021.