In traditional neural network designs, a multilayer perceptron (MLP) is typically employed as a classification block following the feature extraction stage. However, the Kolmogorov-Arnold Network (KAN) presents a promising alternative to MLP, offering the potential to enhance prediction accuracy. In this paper, we studied KAN-based networks for pixel-wise classification of hyperspectral images.
View Article and Find Full Text PDFIn patients with ischemic heart disease, the administration of contrast agents iodixanol, ioversol and gadobutrol improves (due to the effect of dilution) the aggregation of erythrocytes in vivo, but does not change their deformation ability and the percentage of different morphological forms of erythrocytes (discocytes and ehinocytes) in the blood. The effect of gadobutrol on the aggregation of erythrocytes is characterized by more expressed antiaggregant effect due special molecular properties of this drug.
View Article and Find Full Text PDFIt is established that the x-ray contrast agents urografin (76 %), omnipaque-300, optiray-350, ultravist-300, and visipaque-270 produce a dose-dependent decrease in the deformation properties of human erythrocytes in vitro. The degree of manifestation of this negative influence increases with the osmotic activity of agents in the following order: visipaque = ultravist < or = omnipaque < or = optiray < urografin. The effect of these x-ray contrast agents on the deformation of erythrocytes is reversible.
View Article and Find Full Text PDFPatol Fiziol Eksp Ter
January 2008
We studied effects of changed blood theology in cryoglobulinemia on temperature-dependent disorders of peripheral circulation. The rheological status was assessed by aggregation characteristics of blood at temperature 37 degrees C and 4 degrees C at nephelometry of reverse light diffusion. Blood cryoglobulins concentration was determined spectrophotometrically.
View Article and Find Full Text PDFCharacteristic parameters of erythrocyte aggregation/disaggregation kinetics in blood samples of 200 healthy donors at native and standard hematocrit were studied. Average aggregation parameters for men and women at native hematocrit significantly differed, but these differences disappeared after hematocrit standardization, only maximal amplitude of aggregation (I(0)) at standard hematocrit in women was still less than in men (p<0.001).
View Article and Find Full Text PDFA new phospholipid drug "Posphogliv" showed earlier good results in the treatment of liver discases. The mechanism of its effect consists in non-specific repair of biomembranes. In the present study it was used for the treatment of in patients with psoriatic arthritis, accompanied by severe damages of blood rheology.
View Article and Find Full Text PDFClin Hemorheol Microcirc
September 2004
Nephelometry technique was used to register the alterations of the scattering signal from a whole blood sample due to erythrocyte aggregates in stasis and under controlled shear stress. The measured parameters were: the characteristic times of linear and three-dimensional aggregates formation, and the strength of aggregates of different types. These parameters depend on the sample temperature in the range of 2/50 degrees C.
View Article and Find Full Text PDFAim: To study hemorheological status in systemic sclerosis (SS) patients.
Material And Methods: Macro- and microrheology of blood were investigated in 70 SS patients. The rate of spontaneous aggregation of red blood cells [T1(s)], durability of the largest units [Ia2.
Aim: To study blood rheology in patients with psoriatic arthritis (PA) having local or advanced osteolysis.
Materials And Methods: The trial included 16 patients with significant PA and clinical and x-ray symptoms of joint surface osteolysis. Kinetics of red cell aggregation and disaggregation was studied in specially designed erythroagregometer.
The aggregation phenomenon is of great importance for the evaluation of performance of the microcirculation system because of its influence on the blood viscosity at low shear stresses. Some important features and consequences of this phenomenon in vivo can be predicted in the in vitro experiments using optical methods. These methods are considered to be the most informative and applicable not only for the basic study of the aggregation phenomenon, but also for the diagnosis of a number of diseases and for the monitoring of therapeutic treatment in clinics.
View Article and Find Full Text PDFAggregation and disaggregation kinetics of erythrocytes in samples of whole blood were studied using a backscattering nephelometry technique. Blood was drawn from normal subjects and from patients suffering from different diseases: chronic glomerulonephritis, systemic lupus erythematosus, hereditary hypercholesterolemia, pulmonary hypertension, intestinal tumors preoperatively (age > 60 years), psoriasis, psoriatic arthritis, ischemia and ischemia with diabetes. Blood samples of healthy donors were used as controls.
View Article and Find Full Text PDFEksp Klin Farmakol
December 1994
The effects of X-ray contrast agents on human blood rheology were investigated. The main cause of rheological effects of X-ray contrast media is their action on the structure and function of erythrocytes. There was a relationship between the physicochemical properties and the mechanism of action.
View Article and Find Full Text PDFThe new calcium antagonist cerebrocrast intravenously infused in a dose of 0.4 micrograms.kg-1.
View Article and Find Full Text PDFAs many as 39 patients with psoriatic arthritis were examined for hemorheology. Of these, 20 were examined at a time for the status of the microcirculatory bed in the skin and skeletal muscle by 133Xe clearance from the interstitial depot and by laser-Doppler flowmetry at the areas of the clinically intact skin. In 10 patients, the plasma blood viscosity was measured.
View Article and Find Full Text PDFThe authors developed mathematical formulas for the determination of the size of the placenta during the pregnancy based on the technique of ultrasonic scanning. Healthy pregnant females with 19-40 weeks of gestation underwent ultrasonic placentometry. Reference placental volumes were defined.
View Article and Find Full Text PDFBiull Eksp Biol Med
February 1989
Using the ectacytometric method the authors observed that the contrast agents: bilimin, triombrast 76%, iodamide-380, bilignost 20%, bilignost 50%, metrizamide decrease red cell deformability. This effect of the contrast agents depends on their osmolality and chemical structure.
View Article and Find Full Text PDFDermatol Monatsschr
November 1989
Rheological properties of the blood in 50 psoriasis patients were studied during PUVA-therapy. The mean rheological indices in half of the patients were above normal before treatment. During the PUVA-therapy the mean indices in this group of patients were near to normal.
View Article and Find Full Text PDFBiull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR
April 1989
Rheologic blood parameters--fluidity limit tau 0, viscosity n alpha 1, erythrocyte cohesion coefficient (A), hematocrit--were studied in 42 patients with dilated cardiomyopathy (DCM) and 30 patients with ischemic heart disease (IHD) and heart failure of stages I-III. Rheologic parameters tended to increase along with progression of heart failure while in IHD an opposite tendency was observed. Individual analysis in patients with DCM as well as those with IHD demonstrated, irrespectively of the stage of heart failure, both hyper- and hyporheological syndromes.
View Article and Find Full Text PDFFiziol Zh SSSR Im I M Sechenova
November 1985
Macro-rheological features of human blood (the limit of fluidity, seeming viscosity in low shift velocities), cohesion power among erythrocytes, and hematocrit in pregnancy (36-38 weeks), in neonatal period, in acute and chronic heart disease, and in dogs with experimental hemorrhagic shock, were studied. Reduction of the cohesion power among erythrocytes was shown to occur in increase of hematocrit value. If the cohesion power increases it is followed by physiological hemodilution.
View Article and Find Full Text PDFFarmakol Toksikol
November 1984
It has been demonstrated that the radiographic contrast substances (RCS) having a high protein-binding capability, bilignost and endocystobil, exert the most pronounced effects on blood rheological properties, which manifests in an increase in blood fluidity and hydrodynamic strength of aggregates. A reverse, correlation was found between the degree of red cell aggregation and red cell binding with the RCS. The diatrizoate derivatives were shown to have the least significant effects on the rheological properties of the blood.
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