Publications by authors named "Firminger H"
Article Synopsis
- - A young woman experienced rapid breathing difficulties and medical signs pointing to severe lung issues, possibly primary pulmonary hypertension or pulmonary embolism, leading to her acute heart failure.
- - She tragically died six weeks after her symptoms began.
- - An autopsy revealed that she had pulmonary veno-occlusive disease, a rare condition with around 100 documented cases previously.
Article Synopsis
- The infantile form of glycerol kinase deficiency is an X-linked genetic disorder that leads to developmental delays and problems with adrenal hormone production.
- This condition results from a deficiency in outer mitochondrial membrane-bound glycerol kinase, which interferes with the production of glycerophospholipids necessary for steroid hormone synthesis.
- As a consequence, affected individuals may experience insufficient cortisol and mineralocorticoid production, leading to severe issues like stress response failure and potentially dangerous electrolyte imbalances.
Tumors from a large colony of over 2000 Sprague-Dawley rats were reviewed by a panel of pathologists under the auspices of Universities Associated for Research and Education in Pathology, In the course of this study, a distinct malignancy in 105 rats was segregated and given the name "histiocytic sarcoma." This report describes the histologic features and anatomic distribution of the tumor, along with its incidence by age and sex of the rat. The neoplasm is characterized by a spectrum of histologic patterns, one extreme resembling a sarcomatous process and the other a granulomatous process.
View Article and Find Full Text PDFArticle Synopsis
- We are all exposed to various cancer-causing factors that accumulate over time, which can either be repaired or lead to cell death.
- If a mutated cell manages to survive, it can multiply and may be supported by other factors like hormones or infections, overpowering the body’s defenses.
- Meanwhile, our body has protective mechanisms, including enzymes that repair DNA damage and an immune response that targets and destroys cancer cells.
Malignant mesotheliomas were induced in the rat peritoneum by a single injection of chrysotile or crocidolite asbestos fibers. The immediate toxicity of the fibers was noted in both groups of animals, producing approximately 40% mortality, within 8 days after the injection associated with acute peritonities. Tissue reactions to these two types of asbestos were significantly different.
View Article and Find Full Text PDFEpithelioma-like lesion in Lumbricus terrestris after cold injury.
Natl Cancer Inst Monogr
July 1969