Publications by authors named "Firat Koca"

Article Synopsis
  • This study aimed to compare the outcomes, complications, and benefits/downsides of endoscopic versus microscopic stapedotomy surgery, focusing on patients treated from September 2011 to January 2018 at Selcuk University.
  • Both surgical methods resulted in similar improvements in hearing, with no significant difference in postoperative air-bone gaps, but endoscopic stapedotomy had a shorter average operation time and required less manipulation of specific nerves.
  • The findings suggest that endoscopic stapedotomy is a less invasive option with comparable audiological results and complication rates compared to microscopic stapedotomy.
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Objectives: Nasal bone fracture is a frequent entity consulted to the otolaryngologists, approximately accounting for 39% of all facial bone fractures. The most frequent mechanisms of injury consist of assault, sport-related injuries, falls, and motor vehicle accidents. In this study, we examined the effects of the COVID-19 pandemic on pediatric nasal fractures.

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We use single-molecule techniques to characterize the dynamics of prokaryotic DNA repair by non-homologous end-joining (NHEJ), a system comprised only of the dimeric Ku and Ligase D (LigD). The Ku homodimer alone forms a ∼2 s synapsis between blunt DNA ends that is increased to ∼18 s upon addition of LigD, in a manner dependent on the C-terminal arms of Ku. The synapsis lifetime increases drastically for 4 nt complementary DNA overhangs, independently of the C-terminal arms of Ku.

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