Effectiveness of royal jelly on tympanic membrane perforations: an experimental study.

Objective: The aim of this study was to evaluate the comparison of the efficacy of royal jelly in a guinea pig tympanic membrane perforation model with untreated and control groups.

Study Design: Prospective study using 16 adult guinea pigs.

Methods: Each animal underwent subtotal removal of the tympanic membrane in one ear.

[Expression of Ki-67 and p53 in laryngeal squamous cell carcinomas].

Objectives: The aim of this study was to investigate the expression of p53 tumor suppressor gene and Ki-67 antigen in laryngeal squamous cell carcinoma and its relation to conventional prognostic indicators.

Patients And Methods: p53 and Ki-67 expressions were evaluated in surgical specimens of 37 patients (34 males, 3 females; mean age 57.2 years; range 35 to 75 years) with squamous cell carcinoma of the larynx.