Publications by authors named "Firas Abu-Akar"

Article Synopsis
  • The study investigates well-differentiated low-grade lung neuroendocrine tumors (LNETs), focusing on their classification and unique molecular profiles beyond the typical and atypical categories.
  • Researchers used genomic techniques to reveal three distinct regulatory subtypes of LNETs, each characterized by specific transcription factors and differentiation signals: "proneuronal," "luminal-like," and "HNF+."
  • Targeting the FGFR signaling pathway in the HNF+ subtype showed promise for reducing tumor growth, highlighting potential new therapeutic approaches for treating these tumors.
View Article and Find Full Text PDF

Objectives: CALGB140503/JCOG0802 RCTs comparing lobectomy with sublobar resection in stage IA NSCLC have confirmed the non-inferiority of segmentectomy. Additional insight is needed to improve preoperative work-up and intraoperative strategies to increase safety and promote the dissemination of minimally invasive segmentectomy (MIS). A Delphi panel study assessed the level of consensus among surgeons for the planning and management of MIS.

View Article and Find Full Text PDF

Parallel- and cross-bar techniques are surgical methods used in the pectus excavatum. While the parallel bar is used in many centers, the cross bar is a new technique. The aim of the study is to evaluate the data of centers using cross bar and parallel bar.

View Article and Find Full Text PDF
Article Synopsis
  • The SUPER guideline was developed to improve the quality of surgical technique reporting, addressing gaps in existing guidelines to ensure comprehensive documentation across various surgical disciplines and innovations.
  • Created through a collaborative process involving surgeons, editors, and experts from different countries, the guideline includes 22 essential items organized into six sections, covering everything from background and rationale to preoperative preparations and postoperative considerations.
  • The implementation of SUPER aims to enhance transparency in surgical reporting, aiding not just surgeons but also journal editors, reviewers, and practitioners who need clear and reproducible surgical techniques.
View Article and Find Full Text PDF

Uniportal video-assisted thoracic surgery has grown in popularity in recent years, becoming the treatment of choice for minimally invasive resections of mediastinal lesions. The many advantages of video-assisted thoracic surgery, including decreasing postoperative pain, morbidity and length of hospitalization, have increased its utilization for optimal patient care. In our case, this approach was used on a 55-year-old female patient who presented with a retrotracheal mass protruding through the thoracic inlet.

View Article and Find Full Text PDF

Background: It has become apparent that the endoscopic surgeries are rapidly developing, and they have become an essential part of every specialty of surgery. Single port thoracoscopic surgery is developing, enhancing the advantages of muti-portal video-assisted thoracoscopic surgery (VATS). Although becoming a well-recognised approach for adult patients, extremely limited literature exists concerning uniportal VATS among pediatric cases.

View Article and Find Full Text PDF

Objectives: To identify reporting guidelines related to surgical technique and propose recommendations for areas that require improvement.

Study Design And Setting: A protocol-guided scoping review was conducted. A literature search of MEDLINE, the EQUATOR Network Library, Google Scholar, and Networked Digital Library of Theses and Dissertations was conducted to identify surgical technique reporting guidelines published up to December 31, 2021.

View Article and Find Full Text PDF

Low-grade fibromyxoid sarcoma is an extremely rare malignant neoplasm, with an incidence of 0.18 per million, and comprises 0.6% of all soft tissue sarcomas.

View Article and Find Full Text PDF

Background: We aimed at comparing in a multicenter propensity-matched analysis, results of nonintubated versus intubated video-assisted thoracic surgery (VATS) bullectomy/blebectomy for primary spontaneous pneumothorax (PSP).

Methods: Eleven Institutions participated in the study. A total of 208 patients underwent VATS bullectomy by intubated (IVATS) (N = 138) or nonintubated (NIVATS) (N = 70) anesthesia during 60 months.

View Article and Find Full Text PDF

Pectus carinatum may rarely be associated with kyphosis. However, the correlation between both conditions is not well reported. Therefore, there are no reports for combined correction of both deformities in the same patient.

View Article and Find Full Text PDF

Objectives: This study reports the results of an international expert consensus process evaluating the assessment of intraoperative air leaks (IAL) and treatment of postoperative prolonged air leaks (PAL) utilizing a Delphi process, with the aim of helping standardization and improving practice.

Methods: A panel of 45 questions was developed and submitted to an international working group of experts in minimally invasive lung cancer surgery. Modified Delphi methodology was used to review responses, including 3 rounds of voting.

View Article and Find Full Text PDF
Article Synopsis
  • Malignant pleural mesothelioma (MPM) is a serious cancer linked mainly to asbestos, but this case highlights a familial occurrence due to a BAP1 gene mutation, suggesting genetic factors may play a role.
  • The 39-year-old patient experienced severe respiratory issues and was diagnosed using biopsies from Video-Assisted Thoracoscopic Surgery after imaging tests were inconclusive.
  • Key takeaways include the possibility that genetic mutations like BAP1 can influence when the disease appears and its prognosis, along with the insight that F-FDG PET/CT scans may not be the most effective for diagnosing and staging MPM.
View Article and Find Full Text PDF

Background: Although rare in the Western world, the incidence of hydatid disease is still prevalent and strikingly endemic among the Palestinians. Until 2017, surgical treatment of lung pathologies was performed through the traditional incision (open thoracotomy). Uniportal video-assisted thoracoscopic surgery (VATS) approach has recently been applied in the cases of the pulmonary hydatid cysts with very satisfactory results.

View Article and Find Full Text PDF

Objectives: Uniportal video-assisted thoracic surgery (VATS) is well accepted by surgeons for anatomical major lung resections. However, large series evaluating the results, safety and efficacy of the technique for sleeve resections are still lacking. The aim of this study was to examine our experience with the use of uniportal VATS for sleeve resections.

View Article and Find Full Text PDF

Objectives: Our goal was to report the results of the first consensus paper among international experts in uniportal video-assisted thoracoscopic surgery (UniVATS) lobectomy obtained through a Delphi process, the objective of which was to define and standardize the main procedural steps, optimize its indications and perioperative management and identify elements to assist in future training.

Methods: The 40 members of the working group were convened and organized on a voluntary basis by the Uniportal VATS Interest Group (UVIG) of the European Society of Thoracic Surgeons (ESTS). An e-consensus finding exercise using the Delphi method was applied to require 75% agreement for reaching consensus on each question.

View Article and Find Full Text PDF

Compared to the intercostal approach, subxiphoid uniportal video-assisted thoracoscopic surgery (VATS) is considered to be less invasive as it may cause minimal postoperative pain. Besides, it provides an excellent view of the bilateral pleural cavities. In this paper, we describe our technique and overview a 2-year experience results in this approach for the surgical treatment of anterior mediastinal and pulmonary lesions.

View Article and Find Full Text PDF

The attempts to implement the enhanced recovery (ER) program based on multiple specialties to minimize errors and complications in addition to speeding up the patient's treatment and recovery as much as possible. In China mainland, there is no unified hospital system and there are large differences between hospitals' results and protocols. The patient length of stay rate at the Shanghai Pulmonary Hospital (very high-volume referral hospital) is 7 days and may be considered a very good result compared to international rates.

View Article and Find Full Text PDF

The subxiphoid uniportal video assisted thoracoscopic surgery (VATS) is a new interesting approach for the resection of anterior mediastinal masses and lung resections. For this reason in cases with both pathologies is an ideal approach to perform both procedures at the same time without multiple incisions. The evolution in the surgery of thymoma is getting less invasive, from the transsternal thymectomy to the minimally invasive Thoracic surgery improving the recovery of the patients and with satisfactory postoperative results, otherwise the anatomical view of the main structures and the recognition of the vascular anatomy, and his variants is feasible.

View Article and Find Full Text PDF

In recent years, the search for a less invasive and thus, less painful approach has driven technical innovation in modern thoracic surgery. In this context, subxiphoid uniportal approach has emerged as an alternative to avoid intercostal space manipulation and decrease postoperative pain and intercostal nerve chronic impairment. Subxiphoid uniportal major lung resections have been safe and effective procedures when performed by experienced surgeons even in complex cases or unexpected intraoperative situations.

View Article and Find Full Text PDF

Interrupted IVC (also known as Azygos continuation of the inferior vena cava) is a relatively uncommon congenital condition with prevalence 1.5% (0.2-3%) of the general population (Bass .

View Article and Find Full Text PDF