Adverse reaction to local anaesthetics: Is it always allergy?

Objective: Local anaesthetics are very commonly used drugs in dentistry, and people who undergo procedures with local anaesthetics often refer adverse reactions that are not of allergic origin. Considering that in dentistry contact with allergens is very frequent, it is essential to assess the real incidence of allergy to local anaesthetics.

Subjects And Methods: We evaluated a group of 159 patients in whom adverse reaction occurred after procedures with local anaesthetics.

Short-term "in vivo" study on cellular DNA damage induced by acrylic Andresen activator in oral mucosa cells.

Objectives: To analyse through comet assay and micronucleus test the viability and DNA damage occurred in buccal mucosa epithelial cells after a short-term exposure to Andresen activator resin monomers.

Setting And Sample Population: Test group consisting of 26 subjects was treated with Andresen activator; 16 subjects who had never undergone orthodontic treatment were enrolled in the control group.

Material & Methods: Buccal mucosa samples were collected before treatment and after 7, 15, 30, 60 and 90 days.

Piezosurgery versus conventional osteotomy in orthognathic surgery: a paradigm shift in treatment.

The aim of the study was to compare in a randomized controlled clinical trial the use of the piezoelectric osteotomy as an alternative to the conventional approach in terms of surgery time, intraoperative blood loss, cut quality, nerve injury, and costs.One hundred ten patients who had orthognathic surgery procedures with bimaxillary osteotomy were divided into 2 groups: group A was treated with a piezosurgery device, and group B, with a reciprocating saw and bur.The piezosurgical bone osteotomy permitted individualized cut designs.

Support for the role of Candida spp. in extensive caries lesions of children.

Candida spp. are frequently detected in the mouths of children with extensive caries lesions compared with caries-free subjects. In this study we evaluated the presence of Candida spp.

In vivo study on metal release from fixed orthodontic appliances and DNA damage in oral mucosa cells.

Interest in the amount of metal ion intake from dental alloys has grown. Fixed orthodontic appliances usually include brackets, bands, and archwires made of stainless steel, nickel-titanium, or nickel-cobalt alloys, and these can release metal ions. The purpose of this study was to investigate the biocompatibility in vivo of fixed orthodontic appliances, evaluating the presence of metal ions in oral mucosa cells, their cytotoxicity, and their possible genotoxic effects.