Publications by authors named "Fionn McNeill"
The Pd-catalysed decarboxylative asymmetric allylic alkylation (DAAA) has been applied to the enantioselective synthesis of sterically hindered benzofuran-3(2H)-one-derived α-aryl-β-keto esters employing the (R,R)-ANDEN phenyl Trost ligand. A range of substrates were synthesised, employing previously developed aryllead triacetate methodology to install various aryl groups. The resulting α-aryl-α-allyl benzofuran-3(2H)-one DAAA products were obtained in moderate to high yields and in enantioselectivities of up to 96 % ee, with the best results observed for substrates containing a di-ortho-substitution pattern on the aryl ring as well as naphthyl-containing substrates.
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- The study focuses on using ion current rectification (ICR) for sensing applications in aprotic solvents, specifically targeting metal detection in the chemical industry.
- Researchers developed a method using cyclam-functionalized quartz nanopipettes and tetraethylammonium tetrafluoroborate in acetonitrile as a supporting electrolyte to detect trace amounts of palladium (Pd) and cobalt (Co).
- The new method allows for rapid concentration analysis of Pd in organic products, yielding results comparable to traditional techniques like ICP-MS, while requiring less complex sample preparation and functioning effectively at very low concentrations.