Publications by authors named "Fiona Perez"
Background: Functional cognitive disorder (FCD) poses a diagnostic challenge due to its resemblance to other neurocognitive disorders and limited biomarker accuracy. We aimed to develop a new diagnostic checklist to identify FCD versus other neurocognitive disorders.
Methods: The clinical checklist was developed through mixed methods: (1) a literature review, (2) a three-round Delphi study with 45 clinicians from 12 countries and (3) a pilot discriminative accuracy study in consecutive patients attending seven memory services across the UK.
Article Synopsis
- The study examined how cognitive specialists diagnose and manage functional cognitive disorder (FCD) compared to neurodegenerative diseases, using clinical vignettes for assessment.
- Forty-five experts from 12 countries effectively distinguished between FCD and neurodegeneration, accurately diagnosing all neurodegenerative cases, but only 75%-88% of FCD cases were correctly classified due to varied terminology.
- The findings highlight the need for improved agreement on FCD terminology and more research into validation and diagnostic tools, while suggesting that management strategies should include diagnostic communication and referrals for psychotherapy.
Purpose: This joint guideline by American Society for Radiation Oncology (ASTRO) and the European Society for Radiotherapy and Oncology (ESTRO) was initiated to review evidence and provide recommendations regarding the use of local therapy in the management of extracranial oligometastatic non-small cell lung cancer (NSCLC). Local therapy is defined as the comprehensive treatment of all known cancer-primary tumor, regional nodal metastases, and metastases-with definitive intent.
Methods: ASTRO and ESTRO convened a task force to address 5 key questions focused on the use of local (radiation, surgery, other ablative methods) and systemic therapy in the management of oligometastatic NSCLC.