Publications by authors named "Fiona Caroline Malcomson"
Int J Obes (Lond)
February 2022
Article Synopsis
- Obesity is linked to an increased risk of colorectal cancer (CRC), but the impact of weight loss on CRC risk and its relationship with microRNA expression is not well understood.
- Researchers studied microRNA expression in the rectal mucosa of obese patients before and after Roux-en-Y gastric bypass (RYGB) and healthy non-obese controls, finding significant differences in microRNA levels.
- The study revealed that obesity causes abnormal microRNA expression, which can be normalized after significant weight loss from RYGB, potentially influencing pathways related to inflammation, obesity, and cancer risk.
