Changes in the incidence of transfusion reactions in hematological patients over the past 30 years.

Background: Patients with hematological diseases are polytransfused and often immunocompromised, therefore susceptible to transfusion reactions (TR). This study aims to document the incidence of TRs in adult hematological patients and assess the effect of changes in the production of blood components and transfusion practice on their occurrence.

Study Design And Methods: Retrospective observational analysis of TRs reported from 1993 to 2019 was performed.