Publications by authors named "Filippo Castelli"
Article Synopsis
- The Brain Imaging Data Structure (BIDS) is a community-created standard for organizing neuroscience data and metadata, helping researchers manage various modalities efficiently.
- The paper discusses the evolution of BIDS, including the guiding principles, extension mechanisms, and challenges faced during its development.
- It also highlights key lessons learned from the BIDS project, aiming to inspire and inform researchers in other fields about effective data organization practices.
The toxicity of three phthalates (PAEs) - butylbenzyl phthalate (BBP), diethyl phthalate (DEP), and di-(2-ethylhexyl) phthalate (DEHP) - was tested on the Mediterranean sea urchin Paracentrotus lividus. Fertilized eggs were exposed to environmental and high PAE concentrations for 72 h. The potential toxic effects on larval development and any morphological anomalies were then assessed to estimate PAEs impact.
View Article and Find Full Text PDFBrain cells are arranged in laminar, nuclear, or columnar structures, spanning a range of scales. Here, we construct a reliable cell census in the frontal lobe of human cerebral cortex at micrometer resolution in a magnetic resonance imaging (MRI)-referenced system using innovative imaging and analysis methodologies. MRI establishes a macroscopic reference coordinate system of laminar and cytoarchitectural boundaries.
View Article and Find Full Text PDFArticle Synopsis
- The Brain Imaging Data Structure (BIDS) is a collaborative standard designed to organize various neuroscience data and metadata.
- The paper details the history, principles, and mechanisms behind the development and expansion of BIDS, alongside the challenges it faces as it evolves.
- It also shares lessons learned from the project to help researchers in other fields apply similar successful strategies.
The Brain Imaging Data Structure (BIDS) is a specification for organizing, sharing, and archiving neuroimaging data and metadata in a reusable way. First developed for magnetic resonance imaging (MRI) datasets, the community-led specification evolved rapidly to include other modalities such as magnetoencephalography, positron emission tomography, and quantitative MRI (qMRI). In this work, we present an extension to BIDS for microscopy imaging data, along with example datasets.
View Article and Find Full Text PDFBackground: Von Willebrand factor (VWF) levels are regulated by genetic and acquired factors. The acquired factors are mostly related to age and could be mediators of the age effect on VWF levels.
Objectives: To disentangle the role of genetic (sex, blood group) and acquired factors (comorbidities, body mass index, reduced kidney function, hormone use, and inflammation) in regulating von Willebrand factor antigen (VWF:Ag) and factor VIII activity (FVIII:C) levels in the normal population.