Effects of Random Feeding Schedule on Pacing in Asiatic Lions (Panthera leo persicus).

For large felids in the wild, intervals between feeding events are irregular since these depend on prey availability and individual hunting success. In contrast, many zoos feed their large felids on fixed schedules. Predictable feeding schedules could induce food anticipatory behavior, like pacing, and randomizing feeding schedules may reduce this anticipatory behavior.

Development and internal validation of a clinical score to predict neonatal hypoglycaemia in women with gestational diabetes.

Introduction: Gestational diabetes (GD) is a risk factor for neonatal hypoglycaemia (NH), but other factors can increase this risk.

Objectives: To create a score to predict NH in women with GD.

Methods: Retrospective study of women with GD with a live singleton birth between 2012 and 2017 from the Portuguese GD registry.

Case study: Visual barriers reduce pacing in captive tigers.

Captive large felines are prone to abnormal repetitive behaviors like pacing, which are associated with welfare issues. Visual contact without the opportunity to engage in appropriate behavior is known to increase pacing. To better understand the relationship between pacing and conspecific visual contact, we investigated this effect by conducting a barrier experiment on a male-female pair of Sumatran tigers (Panthera tigris sumatrae) in Rotterdam Zoo, the Netherlands.

Association between foetal sex and adverse neonatal outcomes in women with gestational diabetes.

Aims: Foetal male sex is associated with adverse perinatal outcomes. However, studies evaluating the impact of foetal sex on perinatal outcomes in women with gestational diabetes (GDM) are scarce. We studied whether male new-born sex is associated with neonatal outcomes, in women with GDM.

"Mesenteric stripping using a Veress needle: A creative approach to resect small bowel disease in advanced ovarian cancer".

Small bowel involvement in patients with advanced ovarian cancer has been associated with a worse prognosis and recent data suggests it can be an independent factor associated with shorter disease-free interval (Casales Campos et al., 2022). In the upfront cytoreductive setting, small bowel residual disease (serosa and mesentery) has been identified as the most common site of residual disease (Heitz et al.

Low stress hyperglycemia ratio predicts worse prognosis in diabetic acute heart failure patients.

Introduction: Acute blood glucose but not glycated hemoglobin (HbA1c) predicts poor outcome in acute heart failure (HF). The stress hyperglycemia ratio (SHR) has been proposed as a prognostic predictor in various clinical settings.

Objectives: We assessed the prognostic implications of the SHR in acute HF patients with and without diabetes.

CA-125 variation in acute heart failure: a single-centre analysis.

Aims: A decrease in carbohydrate antigen 125 (CA-125) predicts survival advantage in chronic heart failure (HF); the impact of its variation in acute HF is unknown. We studied the association of CA-125 decrease with prognosis in acute HF.

Methods And Results: We studied acute hospitalized HF patients.

The prognostic impact of uric acid in acute heart failure according to coexistence of diabetes mellitus.

Background And Aims: Increased uric acid levels predict higher mortality in heart failure (HF) patients. Patients with diabetes mellitus (DM) appear to have increased xanthine oxidase activity. We aimed to study if the association between uric acid and mortality in acute HF was different according to the coexistence of DM.

Retroileal colorectal anastomosis after left-sided or transverse colectomy for advanced serous carcinoma of the ovary or uterus.

The ability to achieve complete or optimal cytoreduction in advanced or recurrent ovarian and uterine cancer is a well-established prognostic factor. Colonic resections are commonly required to achieve minimal or no residual disease. When multiple colonic resections are required there is a corresponding difficulty in obtaining sufficient colonic mobility to create tension-free anastomoses for restoration of gastrointestinal continuity; specifically, when a left hemicolectomy or a transverse colectomy is required in addition to a rectosigmoid resection, it may be difficult to achieve a tension-free colorectal anastomosis.

Who do you trust? Wild birds use social knowledge to avoid being deceived.

Many species give deceptive warning calls, enabled by the high risk of ignoring them. In Siberian jays, a territorial, group-living bird, individuals give warning calls toward perched predators and mob them. However, intruding neighbors can emit these warning calls in the absence of predators to access food, but breeders often ignore these calls.

Dynamics of growth differentiation factor 15 in acute heart failure.

Aims: Risk stratification in acute heart failure (HF) patients can help to decide therapies and time for discharge. The potential of growth differentiation factor 15 (GDF-15) in HF has been previously shown. We aimed to study the importance of GDF-15-level variations in acute HF patients.

The utility of prolactin serial sampling and the best prolactin cut-offs associated with persistent hyperprolactinemia.

Background: A single prolactin sampling is recommended for the diagnosis of hyperprolactinemia. We aimed to study the utility of the prolactin serial sampling and to determine the best cut-offs associated with persistent hyperprolactinemia.

Methods: Retrospective study of hyperprolactinemic patients [referral prolactin (rPRL)] that underwent prolactin serial samplings.

Glucose variability predicts 6-month mortality in patients hospitalized with acute heart failure.

In diabetes mellitus (DM), glycaemic fluctuations associate with higher oxidative stress than sustained chronic hyperglycaemia and glucose variability increases the risk of chronic diabetic complications. Our hypothesis was that higher glucose variability would associate with mortality after an acute heart failure (HF) episode. We retrospectively analysed patients with DM hospitalized with acute HF between 2009 and 2010.

Metformin combined with insulin in women with gestational diabetes mellitus: a propensity score-matched study.

Aim: Metformin use in gestational diabetes (GDM) is a common practice. Although its use in combination with insulin might be advantageous, it was never formally tested. We studied whether combined treatment was associated with better obstetric or neonatal outcomes compared to insulin alone.

Diabetic patients need higher furosemide doses: a report on acute and chronic heart failure patients.

Introduction: Diuretics are first-line drugs in symptomatic heart failure treatment. Diabetes mellitus has been suggested as a determinant of diuretic resistance. Studies comparing the dose and efficacy of diuretics in patients with and without diabetes are lacking.

The cholesterol paradox may be attenuated in heart failure patients with diabetes.

Background: In heart failure (HF) patients, a lower total cholesterol (TC) appears to portend an ominous prognosis. We studied if the prognostic impact of TC was different according to diabetes mellitus (DM) status in a chronic HF population.

Methods: Patients with systolic HF under optimized and stable evidence-based therapy were prospectively recruited from our HF clinic.

The Effect of the Bariatric Surgery Type on the Levothyroxine Dose of Morbidly Obese Hypothyroid Patients.

Background: Doubts exist about the effect of different bariatric surgery (BS) types on levothyroxine (Lt4) absorption. We compared Lt4 doses and their variation (ΔLt4) in patients with hypothyroidism that underwent malabsorptive (MS) or restrictive (RS) surgery and studied predictors of Lt4 dose change.

Methods: Retrospective study of morbidly obese hypothyroid patients submitted to BS.

The impact of deep brain stimulation on health related quality of life and disease-specific disability in Meige Syndrome (MS).

Meige Syndrome (MS) is a disabling movement disorder which impairs daily routines such as eating and speaking and, when not responsive to best medical treatment, deep brain stimulation (DBS) of the globus pallidus interna (GPi) has been considered. Previous evidence has shown a significant improvement in motor dysfunction with DBS, however its benefit on disease-specific disability and quality of life has not been thoroughly studied. We describe two patients with severe MS submitted to GPi-DBS.