Soil low-density geochemical mapping of technology-critical elements (TCEs) and its environmental implications: The case of lithium in Portugal.

Increased use of technology-critical elements (TCEs) like lithium (Li), and their socio-environmental impacts, make it an issue of national and global importance. In Portugal, new Li exploration/exploitation projects are a very likely scenario. Thus, it is essential to establish geochemical backgrounds/thresholds for Li in soil, which can have several applications.

Composition and sources of sediment organic matter in a western Iberian salt marsh: Developing a novel prediction model of the bromine sedimentary pool.

Salt marshes are sensitive highly productive habitats crucial for carbon cycling. This study presents a comprehensive analysis of organic geochemical indicators and geochronology in the Mira salt marsh (SW Portugal) over eight centuries. The closely intertwined carbon and bromine (Br) biogeochemical cycles in these environments can influence the fluxes of volatile compounds such as ozone-depleting methyl bromide, emphasizing the importance of understanding sediment organic matter (OM) origin, budget, and composition in salt marshes.

Pre-vaccination immune response to COVID-19 in a population in Northeast Portugal.

Purpose: To study the immunization status and IgM and IgG antibody behavior against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an unvaccinated population of Northeast Portugal (including RT-PCR diagnosed and undiagnosed individuals).

Methods: Application of a clinical-epidemiological survey, and analysis of IgM and IgG SARS-COV-2 antibodies (against N core protein) in 362 participants that voluntarily sought the laboratory for testing.

Results: At the time of the analysis, 31.

Breast Tumours Resembling the Tall Cell Variant of Thyroid Papillary Carcinoma: Are They Part of the Papillary Carcinoma Spectrum or a Distinct Entity?

Background: Papillary tumours of the breast are diagnostically challenging lesions and represent a wide spectrum of diseases from papilloma to invasive papillary carcinoma. A rare subtype of breast papillary tumour resembling the tall cell variant of thyroid papillary carcinoma (BTRTPC) has been described. The nomenclature of this entity, its relationship to other papillary tumours, and its nature, whether in situ or invasive, remain unclear.

Invasion in breast lesions: the role of the epithelial-stroma barrier.

Despite the significant biological, behavioural and management differences between ductal carcinoma in situ (DCIS) and invasive carcinoma of the breast, they share many morphological and molecular similarities. Differentiation of these two different lesions in breast pathological diagnosis is based typically on the presence of an intact barrier between the malignant epithelial cells and stroma; namely, the myoepithelial cell (MEC) layer and surrounding basement membrane (BM). Despite being robust diagnostic criteria, the identification of MECs and BM to differentiate in-situ from invasive carcinoma is not always straightforward.

Infantile myofibromatosis - a clinical and pathological diagnostic challenge.

Infantile myofibromatosis is a rare disorder of fibroblastic/myofibroblastic proliferation and represents the most frequent type of mesenchymal tumor in the neonatal period and primary infancy.Three clinical types have been described: solitary, multicentric, and generalized (with visceral involvement). A correct characterization of the histopathology is essential to diagnose these neoplasias in early infancy.

Systemic mastocytosis with V560G mutation presenting as recurrent episodes of vascular collapse: response to disodium cromoglycate and disease outcome.

Background: Mastocytosis are rare diseases characterized by an accumulation of clonal mast cells (MCs) in one or multiple organs or tissues. Patients with systemic mastocytosis (SM), whose MCs frequently arbor the activating D816V mutation, may have indolent to aggressive diseases, and they may experience MC mediator related symptoms. Indolent SM with recurrent anaphylaxis or vascular collapse in the absence of skin lesions, ISMs(-), is a specific subtype indolent SM (ISM), and this clonal MC activation disorder represents a significant fraction of all MC activation syndromes.

17-Week Delay Surgery after Chemoradiation in Rectal Cancer with Complete Pathological Response.

Neoadjuvant chemoradiation (CRT) followed by curative surgery still remains the standard of care for locally advanced rectal cancer (LARC). The main purpose of this multimodal treatment is to achieve a complete pathological tumor response (ypCR), with better survival. The surgery delay after CRT completion seems to increase tumor response and ypCR rate.

Primary gastric choriocarcinoma: A rare case.

Introduction: Primary gastric choriocarcinoma accounts for 0.08% of all gastric cancers. It is a rapidly growing, widely metastatic and β-HCG-producing tumour of trophoblastic cells.

Splenic metastasis from gastric adenocarcinoma: A rare case.

Introduction: Isolated splenic metastasis are very rare. There are only a few reported cases of patients with isolated splenic metastasis from gastric primary tumors.

Presentation Of Case: We present a case of a 71-year-old patient with isolated splenic metastasis, diagnosed 6 years after primary treatment of a gastric adenocarcinoma, who previously had a lung resection also for metastasis.