Publications by authors named "Filip Lyng Lindgren"
Article Synopsis
- Many COPD patients are diagnosed late, often during their first acute exacerbation (AECOPD), which increases mortality risk.
- In a study of over 107,000 patients, those diagnosed in primary care were younger, while those identified in hospitals were older, mostly male, and had more comorbidities.
- Hospital diagnoses were linked to higher one-year mortality rates compared to earlier diagnoses in primary care, emphasizing the importance of timely diagnosis.
Article Synopsis
- Left atrial (LA) strain assessed by three-dimensional echocardiography (3DE) offers a more precise way to gauge LA function compared to traditional two-dimensional methods, which can be important for predicting health risks.
- A study with 4,466 participants, of which 1,935 had their LA strain analyzed, found that over a median follow-up of 4.8 years, 3% developed atrial fibrillation (AF), and significant associations were made between certain strain measures and the onset of AF.
- Specifically, LA reservoir strain (LASr) and contractile strain (LASct) were linked to increased AF risk, providing valuable prognostic information that goes beyond existing clinical risk assessment tools.
Background: Cardiac magnetic resonance imaging (cMRI) is considered the gold standard for the assessment of left ventricular (LV) systolic function. However, discrepancies have been reported in the literature between LV volumes assessed by transthoracic echocardiography (TTE) and cMRI. The objective of this study was to analyze the differences in LV volumes between different echocardiographic techniques and cMRI.
View Article and Find Full Text PDFThis study used demographic data in a novel prediction model to identify areas with high risk of out-of-hospital cardiac arrest (OHCA) in order to target prehospital preparedness. We combined data from the nationwide Danish Cardiac Arrest Registry with geographical- and demographic data on a hectare level. Hectares were classified in a hierarchy according to characteristics and pooled to square kilometers (km2).
View Article and Find Full Text PDFNormal values for left atrial strain, volume, and function derived from 3D echocardiography: the Copenhagen City Heart Study.
Eur Heart J Cardiovasc Imaging
April 2024
Aims: 3D echocardiographic (3DE) assessment of the left atrium (LA) is a new modality of potential clinical value. Age- and sex-based normative values are needed to benchmark these parameters for clinical use.
Methods And Results: Of 4466 participants in the 5th Copenhagen City Heart Study, a prospective longitudinal cohort study on the general population, 2082 participants underwent 3DE of the LA.
Assessment of the left ventricular (LV) function by three-dimensional echocardiography (3DE) is potentially superior to 2D echo echocardiography (2DE) for LV performance assessment. However, intra- and interobserver variation needs further investigation. We examined the intra- and interobserver variability between 2 and 3DE in a general population.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to validate the National Danish Ablation Database (NDAD) by comparing its data on patients who underwent ablation for atrial fibrillation against their medical records.
- Researchers included 597 patients and assessed positive predictive values (PPV) and negative predictive values (NPV) across different categories, finding high agreement with both PPV and NPV exceeding 90%.
- Results indicated that NDAD has strong validity, with data aligning well with medical records, although the low complication rates led to slightly less certainty in the PPV and NPV related to complications.
The long-term cardiovascular risk for patients examined with coronary computed tomography angiography (CCTA) to rule out coronary heart disease compared with population controls remains unexplored. A nationwide register-based study including first-time CCTA-examined patients between 2007 and 2017 in Denmark alive 180 days post-CCTA was conducted. We evaluated 5-year outcomes of myocardial infarction (MI) or revascularization and all-cause mortality in 3 distinct CCTA-groups: (1) no post-CCTA preventive pharmacotherapy use (cholesterol-lowering drugs, antiplatelets, or anticoagulants); (2) post-CCTA preventive pharmacotherapy use; and (3) revascularization or MI within 180 days post-CCTA.
View Article and Find Full Text PDFBackground: Geographical setting is seldomly taken into account when investigating out-of-hospital cardiac arrest (OHCA). It is a common notion that living in rural areas means a lower chance of fast and effective helpwhen suffering a time-critical event. This retrospective cohort study investigates this hypothesis and compares across healthcare-divided administrative regions.
View Article and Find Full Text PDFPeriprocedural complications and one-year outcomes after catheter ablation for treatment of atrial fibrillation in elderly patients: a nationwide Danish cohort study.
J Geriatr Cardiol
November 2021
Article Synopsis
- The study examined complications within 30 days of first-time catheter ablation for atrial fibrillation (AF) in patients aged ≥ 75 years compared to those aged 65-74 years.
- No significant difference in the rate of complications, including cardiac issues and death, was found between the two age groups, indicating similar safety profiles.
- Additionally, there was no notable difference in one-year AF relapse rates, suggesting that older patients do not face higher risks or reduced effectiveness from the procedure compared to younger patients.
Objective: Incidence and severity of acute myocarditis vary significantly in previous reports and there is a lack of epidemiological studies on the short-term risks of mortality, heart failure and ventricular arrhythmias in patients with acute myocarditis. Therefore, study aims were to examine 90-day risks of mortality, heart failure (HF) and ventricular arrhythmias in patients with acute myocarditis in comparison to age-matched and sex-matched background population controls.
Methods: In this nationwide register-based follow-up study of patients hospitalised with myocarditis between 2002 and 2018 in Denmark, 90-day risks of all-cause mortality, HF, ventricular arrhythmias (ventricular tachycardia, ventricular fibrillation (VF)), cardiac arrest and implantable cardioverter-defibrillator (ICD) implantation were compared with age-matched and sex-matched controls from the background population (1:5 matching).