Publications by authors named "Filip Hruby"
Article Synopsis
- Despite progress in vaccinations, COVID-19 remains a significant risk for kidney transplant recipients (KTRs) due to their weakened immune response.
- A study of 120 KTRs revealed that their ability to produce neutralizing antibodies after receiving a booster shot of the mRNA vaccine BNT162b2 was noticeably lower and declined more rapidly than that of healthy individuals.
- Factors like age, reduced kidney function, and the use of mycophenolate mofetil were linked to this decreased antibody production, but overall, the type of antibodies produced was similar to those found in healthy subjects, without cross-reactivity to seasonal coronaviruses.
Introduction: There is a strong impetus for the use of telemedicine for boosting early detection rates and enabling early treatment and remote monitoring of COVID-19 cases, particularly in chronically ill patients such as kidney transplant recipients (KTRs). However, data regarding the effectiveness of this practice are lacking.
Methods: In this retrospective, observational study with prospective data gathering we analyzed the outcomes of all confirmed COVID-19 cases ( = 955) in KTRs followed at our center between March 1, 2020, and April 30, 2022.