Oral pemphigus vulgaris diagnostic characteristics and treatment: a systematic review.

Pemphigus vulgaris (PV) is a rare, potentially fatal, immune-mediated chronic disease characterized by the presence of bullous intraepithelial lesions on mucous membranes and skin. This study aimed to perform a systematic literature review covering PV clinical and histopathological aspects and treatment. The literature searches were carried out in the Pubmed, Periódicos Capes, Scopus, Science Direct, Web of Science and Scielo databases.

Comparative Analysis of Machine Learning Techniques for Identifying Multiple Force Systems from Accelerometer Measurements.

The knowledge of the forces acting on a structure enables, among many other factors, assessments of whether the component's useful life is compromised by the current machine condition. In many cases, a direct measurement of those forces becomes unfeasible, and an inverse problem must be solved. Among the solutions developed, machine learning techniques have stood out as powerful predictive tools increasingly applied to engineering problem-solving.

Methanolic Extract of (Rhizophoraceae) Leaves: Phytochemical Characterization and Anthelmintic Evaluation against .

is commonly used in traditional medicine to treat infections, reduce inflammation, and promote healing. This study aimed to analyze the phytochemical profile of the methanolic extract of leaves (MELRm) and evaluate its in vitro schistosomicidal activity against as well as its cytotoxicity. Plant material was collected in Itamaracá City, Pernambuco, Brazil.

Antimicrobial and antibiofilm properties of procyanidins: potential for clinical and biotechnological applications.

Procyanidins (PCs) have emerged as agents with potential antimicrobial and antibiofilm activities, although their mechanisms of action and structure-activity relationships remain poorly understood. This review assessed the potential mechanisms of action and applications of these compounds to explore these aspects. Studies on the antimicrobial properties of PCs suggest that they are involved in osmotic imbalance, DNA interactions and metabolic disruption.

Workload and spirometry associated with untethered swimming in horses.

Background: Swimming has been used empirically for rehabilitation and conditioning of horses. However, due to challenges imposed by recording physiological parameters in water, the intensity of free swimming effort is unknown.

Objectives: Measure the physiological workload associated with untethered swimming in horses.

Regression models from portable NIR spectra for predicting the carcass traits and meat quality of beef cattle.

The aims of this study were to predict carcass and meat traits, as well as the chemical composition of the 9th to 11th rib sections of beef cattle from portable NIR spectra. The 9th to 11th rib section was obtained from 60 Nellore bulls and cull cows. NIR spectra were acquired at: P1 -center of Longissimus muscle; and P2 -subcutaneous fat cap.

Synthesis, Characterization, and Evaluation of the Antimicrobial Effects and Cytotoxicity of a Novel Nanocomposite Based on Polyamide 6 and Trimetaphosphate Nanoparticles Decorated with Silver Nanoparticles.

This study aimed to develop a polymeric matrix of polyamide-6 (P6) impregnated with trimetaphosphate (TMP) nanoparticles and silver nanoparticles (AgNPs), and to evaluate its antimicrobial activity, surface free energy, TMP and Ag release, and cytotoxicity for use as a support in dental tissue. The data were subjected to statistical analysis ( < 0.05).

Designing, development and validation of an app to reduce the response time of the emergency medical services.

Introduction: Delays in prehospital care attributable to the call-taking process can often be traced back to miscommunication, including uncertainty around the call location. Geolocation applications have the potential to streamline the call-taking process by accurately identifying the caller's location.

Objective: To develop and validate an application to geolocate emergency calls and compare the response time of calls made via the application with those of conventional calls made to the Brazilian Medical Emergency System (Serviço de Atendimento Médico de Urgência-SAMU).

Oocyte competence and gene expression in parthenogenetic produced embryos from repeat breeder and normally fertile buffaloes (Bubalus bubalis) raised in sub-humid tropical climate.

The reproductive management of the buffalo species still faces several unresolved problems, which directly affect the productivity of the herd, one of them being the presence of repeat breeder females. Given this scenario, this study aimed to verify the developmental competence of oocytes obtained from repeat breeder females and submitted to parthenogenetic activation. In addition, embryo gene expression was compared to normally fertile females.

Factors affecting the embryo production in buffalo (): A review.

Under natural and well-managed conditions, the buffalo has good reproductive and productive indices. However, embryo production (IVEP) has been used commercially to maximise the number of elite animals. In this species, several factors (donor management, culture medium, semen, conditions, embryo transfer) still affect the IVEP results.

Experimental Study of Drilling Damage Outcomes in Hybrid Composites with Waste Micro-Inclusions.

Composite materials are used in a substantial number of products. Environmental concerns highlight the need for the inclusion of recovered waste in their formulation, thus reducing their carbon footprint. These solutions raise the need to confirm the mechanical characteristics of these materials, avoiding unwanted failures.

Does vitamin blends supplementation affect the animal performance, carcass traits, and nutrient digestibility of young Nellore finishing bulls?

Objective: This study was realized to evaluate the effects of supplementation with blends of water and fat-soluble vitamins on animal performance and carcass traits of young Nellore bulls.

Methods: Forty-three Nellore bulls, with an initial weight of 261±27.3 kg and a mean age of 8±1.

Re-orientating systematic reviews to rigorously examine what works, for whom and how: Example of a realist systematic review of school-based prevention of dating and gender violence.

Conventional systematic reviews offer few insights into for whom and how interventions work. 'Realist reviews' examine such questions via examining 'context-mechanism-outcome configurations' (CMOCs) but are insufficiently rigorous in how evidence is identified, assessed and synthesised. We developed 'realist systematic reviews', addressing similar questions to realist reviews but using rigorous methods.

Birthweight, postnatal growth and blood pressure in adolescents of low socioeconomic condition: a cohort study in Northeast Brazil.

Objective: To verify the influence of low birth weight and rapid postnatal weight gain and associated factors on blood pressure in adolescence in a population of low socioeconomic status, considering that injuries occur in the perinatal period can be predictors of future metabolic changes and are still poorly explored.

Methods: A cohort study was carried out with 208 adolescents, 78 born with low weight and 130 born with appropriate weight. The infants were followed up during the first six postnatal months and reassessed at 8 and 18 years of age.

Free Swimming and Exercise-Induced Pulmonary Hemorrhage in Endurance Horses: A Preliminary Study.

Swimming is used for rehabilitation of musculoskeletal injuries and for conditioning to improve equine fitness. However, there are anecdotal reports that suggest that tethered swimming can induce epistaxis, likely secondary to exercise-induced pulmonary hemorrhage (EIPH). The objective of this observational, prospective study was to investigate if EIPH occurs during intensive free-swimming training sessions (5 × 70m) using 15 endurance horses.

Systematic review of pharmacological management in Creutzfeldt-Jakob disease: no options so far?

Background: The Creutzfeldt-Jakob disease (CJD) is a spongiform encephalopathy that manifests as a rapidly progressive dementia syndrome. Currently, CJD has no cure, and many patients die within the first year, but some drugs are being studied as options for managing this condition.

Objective: To evaluate the effectiveness of pharmacological treatments offered to patients with CJD as a means to increase survival and reduce cognitive deterioration.

Clinical, Radiographic and Histopathological Analysis of Craniopharyngiomas and Ameloblastomas: A Systematic Review.

Background: Craniopharyngiomas and ameloblastomas are tumors of epithelial origin, mostly characterized by a benign course, slow growth and for being locally invasive. Some studies highlight the similarity of these neoplasms, especially regarding histopathological aspects. In this context, the aim of the present study was to carry out a systematic literature review correlating the clinical, radiographic, and histopathological aspects of these two tumors.

Differential gene expression profile of multinodular goiter.

Introduction: The goiter, a neglected heterogeneous molecular disease, remains a major indication for thyroidectomies in its endemic regions.

Objectives: This study analyzed differential gene expression in surgical specimens diagnosed with multi nodular and compared the data to that of thyroid tissue without multinodular goiter from patients undergoing thyroidectomy in Manaus-AM, Brazil using RNA-seq technology.

Methodology: The transcriptome information of the surgical specimen fragments with and without multinodular goiter was accessed by Illumina HiSeq 2000 New Generation Sequencing (NGS) using the RNA-seq NEBNext® Ultra™ RNA Library Prep Kit for Illumina®-#E7530L protocol and differential gene expression analysis.

Nitrogen excretion from beef cattle fed a wide range of diets compiled in an intercontinental dataset: a meta-analysis.

Manure N from cattle contributes to nitrate leaching, nitrous oxide, and ammonia emissions. Measurement of manure N outputs on commercial beef cattle operations is laborious, expensive, and impractical; therefore, models are needed to predict N excreted in urine and feces. Building robust prediction models requires extensive data from animals under different management systems worldwide.

Temporal and vertical variation of phytoplankton and zooplankton in two tropical reservoirs with different trophic states.

In tropical reservoirs, limnological factors are responsible for changes in plankton and vary at temporal and vertical scales. The aim of this study was to evaluate the effects of temporal and vertical variation of the water column on phytoplankton and zooplankton dynamics in two tropical reservoirs (mesotrophic and supereutrophic) in Northeastern Brazil. Monthly collections from three depths in the limnetic region of the reservoirs were performed to analyze the phytoplankton, zooplankton, and limnological variables.

Kinematic Analysis During Straight Line Free Swimming in Horses: Part 2 - Hindlimbs.

Background: Swimming is used for rehabilitation and conditioning purposes in equine sports medicine. We described the swimming kinematics of the equine forelimbs in Part 1. The aim of Part 2 is to assess stifle, tarsus, and hind fetlock joints kinematics in swimming horses.

Tolerance of Hymenaea courbaril L. to glyphosate.

The objective was to evaluate the effect of the glyphosate on Hymenaea courbaril L. A randomized block design with five replications was implemented. Each experimental unit was composed of one plant in a 5 L container.