Publications by authors named "Filho J"

Instabilities in energy supply caused by equipment failures, particularly in power transformers, can significantly impact efficiency and lead to shutdowns, which can affect the population. To address this, researchers have developed fault diagnosis strategies for oil-immersed power transformers using dissolved gas analysis (DGA) to enhance reliability and environmental responsibility. However, the fault diagnosis of oil-immersed power transformers has not been exhaustively investigated.

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This study analyzed recent changes in the utilization of allogeneic HCT for treatment of acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and myeloproliferative diseases (MPD) and the survival of HCT recipients ≥60 years of age in Brazil. This retrospective registry study included patients who received a first allogeneic HCT from any donor between 2012 and 2023. Of the 6657 patients, 444 (7%) were 60 years of age or older who received grafts from HLA-matched related (42%) or unrelated (20%) donors or HLA-haploidentical donors (32%).

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Background: Facial analysis for orthognathic surgery aims to identify facial features and determine how occlusion should be corrected to achieve facial balance. Several artificial neural networks have been developed to detect facial landmarks; however, no publications have reported the application of neural networks to measure facial proportions specifically for orthognathic surgery planning. Objectives: To develop a computer program that automates facial measurements through photograph capture, as well as to present the development stages of the program and the test results evaluating its effectiveness.

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Background: To describe a case of a patient with PFP after orthognathic surgery and discuss cases reports on temporary or permanent facial paralysis, factors that trigger injury, and treatment for facial paralysis associated with orthognathic surgery.

Material And Methods: This study has two parts: a report of the case of a 20- year-old man who underwent orthognathic surgery for facial paralysis, and an integrative literature review on postoperative facial paralysis following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statements and performed survival analyses of all cases reported to date.

Results: The analysis was composed of 33 patients; 54,5% were male (mean age, 25 years).

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The variability in genetic variance and covariance due to genotype × environment interaction (G×E) can hinder genotype selection accuracy, especially for complex traits. This study analyzed G×E interactions in cassava to identify stable, high-performing genotypes and predict agronomic performance in untested environments using factor analytic multiplicative mixed models (FAMM) within multi-environment trials (METs). We evaluated 22 cassava genotypes for fresh root yield (FRY), dry root yield (DRY), shoot yield (ShY), and dry matter content (DMC) across 55 Brazilian environments.

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This study investigated the effects of recurrent water deficit on drought tolerance traits in black pepper ( L.) 'Bragantina'. Plants were subjected to three cycles of water deficit followed by recovery periods.

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Split hand-foot malformation (SHFM) is a congenital limb malformation affecting primarily the central rays of the hands and/or feet, with variable expressivity, incomplete penetrance and syndromic forms. It is genetically heterogeneous, including point mutations and structural variants in different loci. Five individuals with SHFM were clinically evaluated in a Tertiary Center in Brazil: four of them presented additional, nonskeletal findings, including one individual with split foot, hand syndactyly, and ectodermal findings.

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Background: Neurosurgical training requires a deep understanding of brain anatomy, especially white matter fiber pathways, to enhance surgical precision. Traditional dissection techniques, such as Klingler's white matter dissection, are essential, but newer methods can provide additional clarity. This study explores the application of a fluorescent-assisted technique to improve the visualization and understanding of white matter fibers during neurosurgical training.

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Acute, uncontrolled and/or long-lasting inflammation causes a breakdown in immunological tolerance, leading to chronicity and contributing to a series of significant local or systemic tissue changes. Anti-inflammatory efficacy, fewer adverse effects, improved selectivity, and curative action are imminent issues for patients suffering from chronic inflammation-related pathologies. Then, we performed a complete and critical review about anthelmintics, discussing the main classes and the available preclinical evidence on repurposing to treat inflammation-based conditions.

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Background: The 24-h urine protein (24-hUP) excretion is the gold standard for evaluating proteinuria. This study aimed to evaluate the diagnostic efficacy of protein/creatinine ratio (PCR) for estimating 24-hUP at various levels of renal function and proteinuria levels.

Methods: A cross-sectional study was conducted between December 2021 and December 2023 in Salvador, Bahia-Brazil, as an extension of previously published data from the TUNARI study.

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Article Synopsis
  • * Researchers collected and analyzed tear samples from 30 KC patients and 23 controls, measuring levels of various cytokines and gene expression using techniques like flow cytometry and PCR.
  • * While higher levels of IL-5 and IL-6 were found in KC patients' conjunctival epithelium, there were no significant differences in cytokine concentrations in tear films between the two groups, though some gene expressions were elevated in the KC group.
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Personalized brain implants have the potential to revolutionize the treatment of neurological disorders and augment cognition. Medical implants that deliver therapeutic stimulation in response to detected seizures have already been deployed for the treatment of epilepsy. These devices require low-power integrated circuits for life-long operation.

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Article Synopsis
  • - Receptor tyrosine kinases (RTKs) play crucial roles in cell functions like growth and differentiation, and when their signaling is disrupted, it can lead to tumors and make treatments less effective.
  • - This study analyzed gene expressions of specific RTKs (TAM, RON, EPHA2, and MET) in breast cancer tissues using qPCR, focusing on how these expressions relate to clinical data.
  • - Findings suggest that the expression of TYRO3, MET, and EPHA2 is associated with factors like tumor subtype, patient age, and lifestyle choices such as smoking and obesity, indicating their potential significance in breast cancer.
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  • This study looks at a way to help horses that have a condition called hyperchloremic metabolic acidosis, which is when their body has too much acid.
  • Researchers tested two different drinks for horses with varying amounts of a substance called acetate to see if they could fix the problem.
  • The results showed that one drink with a high level of acetate worked well to balance the horses' electrolytes and help them feel better.
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Industrial effluents, especially those containing dyes, have become the main cause of contamination of water resources. In this context, Brazilian bentonite/MgO composites, with excellent adsorptive properties, were prepared and investigated for their effectiveness in removing cationic and anionic dyes from aqueous solutions. The new adsorbents were obtained using Brazilian bentonites and MgO using the mechanochemical method followed by heat treatment (at 700 °C for 4 h).

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Synthetic antimicrobial peptides (SAMPs) present the potential to fight systemic fungal infections. Here, the PHO36 receptor from was analyzed by tools as a possible target for three anticandidal SAMPs: Alb-PepIII, PepGAT and PepKAA. Molecular docking, dynamics and quantum biochemistry were employed to understand the individual contribution of amino acid residues in the interaction region.

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New methods are essential to characterize the performance of substitute procedures for detecting therapeutic action(s) of a chemical or key signal of toxicological events. Herein, it was discussed the applications and advantages of using arthropods, worms, and fishes in pharmacological and/or toxicology assessments. First of all, the illusion of similarity covers many differences between humans and mice, remarkably about liver injury and metabolism of xenobiotics.

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The development of hydroxyapatite (HAp) and polyether ether ketone (PEEK) biocomposites has been extensively studied for bone repair applications due to the synergistic properties of the involved materials. In this study, we aimed to develop HAp/PEEK biocomposites using high-energy ball milling, with HAp concentrations (20%, 40%, and 60% /) in PEEK, to evaluate their physicochemical, mechanical, cytotoxicity, and antimicrobial properties for potential applications in Tissue Engineering (TE). The biocomposites were characterized by structure, morphology, apparent porosity, diametral compression strength, cytotoxicity, and antimicrobial activity.

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Enteropathogenic (EPEC) are pathogens associated with gastrointestinal illnesses. Dogs and cats can harbor EPEC, and antimicrobial resistance may impair necessary treatments. This study characterized strains from dogs and cats, focusing on phylogroup classification, virulence factors, and antimicrobial resistance profiles.

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Osteoarthritis (OA) is characterized by articular cartilage degeneration, synovial inflammation, and subchondral bone thickening, affecting the synovial joint as an organ and leading to pain and disability. Subcutaneous stromal vascular fraction is safe and relieves pain, improves function, and repairs cartilage defects in patients with knee OA. Our goal is to describe step-by-step the arthroscopic treatment of mild to moderate knee OA with photo-stimulated stromal vascular fraction harvested from the thigh using a selective tissue engineering photo-stimulation ("One S.

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Effects of sleep on procedural (implicit) memory consolidation in children remain controversial. The aim of this systematic review was to synthesise the evidence on the influence of sleep on motor skills acquisition in children. Four electronic databases were searched: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Excerpta Medica Database (Embase), and Biblioteca Virtual em Saúde (BVS).

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In the last decade, extensive and borderless viral disease outbreaks have been caused by Ebola, Zika, and SARS-CoV-2 [...

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Background: Uncorrected myopia is a leading cause of blindness globally, with a rising prevalence in recent decades. Pathological myopia, often seen in individuals with increased axial length (AXL), can result in severe structural changes in the posterior pole, including myopic tractional maculopathy (MTM). MTM arises from tractional forces at the vitreoretinal interface, leading to progressive macular retinoschisis, macular holes, and retinal detachment (RD).

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Accurate transverse deformation measurements are required for the estimation of the Poisson function and volume ratio. In this study, pure silicone and soft composite specimens were subjected to uniaxial tension, and the digital image correlation method was used to measure longitudinal and in- and out-of-plane transverse stretches. To minimize the effects of measurement errors on parameter estimation, the measured transverse stretches were defined in terms of the longitudinal stretch using a new formulation based on Poisson's ratios and two stretch-dependent parameters.

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Holoprosencephaly (HPE) results from a lack of cleavage of the prosencephalon. It has a complex etiology, resulting from chromosome abnormalities or single gene variants in the Sonic hedgehog signaling pathway. A single variant, p.

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