Publications by authors named "Filho AD"

Machine learning (ML) is a promising tool in assisting clinical decision-making for improving diagnosis and prognosis, especially in developing regions. It is often used with large samples, aggregating data from different regions and hospitals. However, it is unclear how this affects predictions in local centers.

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Article Synopsis
  • Coccidioidomycosis, a fungal disease prioritized by the WHO, is frequently underreported in Central and South America, despite being endemic in the U.S. and Mexico.
  • A study in Brazil's Piauí and Maranhão states discovered 292 cases and 42 outbreaks from 1978-2021, predominantly affecting male armadillo hunters, with common symptoms including cough and fever.
  • The analysis indicates that lower rainfall increases disease incidence, and unique genetic strains of the fungus in Brazil suggest potential differences in how the disease behaves compared to other regions.
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Background: Neurotropism of the hepatitis C virus (HCV) can be the source of subtle neuropsychological symptoms in non-cirrhotic patients. Age is a risk factor for cognitive impairment (CI). Thus, asymptomatic elderly people who carry HCV might be at a greater risk of CI.

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Background: Carbapenem-resistant Enterobacterales (CRE) colonisation at liver transplantation (LT) increases the risk of CRE infection after LT, which impacts on recipients' survival. Colonization status usually becomes evident only near LT. Thus, predictive models can be useful to guide antibiotic prophylaxis in endemic centres.

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Background: Anxiety symptoms (AS) are exacerbated in healthcare workers (HCWs) during the COVID-19 pandemic. Spirituality is known to protect against AS in the general population and it is a construct that differs from religion. It can be assessed using structured questionnaires.

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Objectives: Bioimpedance analysis is a simple, safe, and relatively inexpensive method to assess body composition. The bioimpedance guidelines recommend that the test be performed after fasting and avoiding the consumption of liquids. Studies have verified the effects of consuming liquids and food on bioimpedance; however, these studies used preestablished meals and hydration.

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Objectives: The More Doctors Program (MDP) is an ongoing Brazilian policy that aims to improve healthcare by providing physicians to the most vulnerable municipalities. We aimed to measure the impact of MDP in mortality and infant mortality rate, the proportion of live births with low weight, prenatal appointments, childbirths at first and fifth min Apgar, public health investment and immunization in Brazil.

Methods: Municipal health indicators were collected before and after the intervention (2012 and 2015).

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Exosomes, a class of extracellular vesicles, are released by eukaryotes, bacteria, and archaea, as evident from both in vitro and in vivo studies. These nano-sized double-membraned vesicles play an important role in cell-to-cell communication, dysregulation of the immune system, and pathogenesis in a number of diseases, including leishmaniasis. Leishmania is a genus of obligate intracellular parasites, which infect host macrophages, are transmitted through the bite of a sandfly, and are shown to secrete exosomes with immunomodulatory activities.

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Objective: The aim of the present study was to evaluate the agreement between the most used skinfold thickness equations with multi-frequency bioimpedance analysis in the prediction of body fat levels in children.

Method: A cross-sectional study of healthy Brazilian community-dwelling individuals. The anthropometric assessment included height, body mass, arm circumference, and waist circumference.

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Objective: To evaluate the relationship between physical activity and phase angle.

Design: Systematic Review and Meta-analysis.

Data Sources: Electronic searches of MEDLINE (via PUBMED), EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library), SciELO, LILACS, SPORTDiscus, Scopus, and Web of Science from inception to December 10th, 2017.

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Objectives: To analyze factors associated with age at natural menopause in elderly women who are part of the Health, Well-Being and Aging Study- which is a representative sample of elderly residents of the municipality of São Paulo, Brazil.

Methods: Multivariate Cox proportional-hazards analysis using data from a total of 1,415 women with natural menopause. We included 163 women with hysterectomy, oophorectomy, and estrogen therapy as censored data.

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The purpose of this study was to identify the risk factors that predispose patients who are hospitalized with pressure ulcers (PUs) colonized by Gram-negative bacilli (GNB) to develop bacteremia. In addition, we also detected main phenotypes of resistance in infected and uninfected PUs. A prospective cohort study was conducted at the Clinical Hospital of the Federal University of Uberlândia including patients with Stage II or greater PUs, colonized or not with GNB, from August 2009 to July 2010.

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Background: Atrioventricular reentrant tachycardias account for approximately one third of cases referred for electrophysiological study (EPS). The anatomical substrate responsible for the reentry is an accessory pathway (AP) able to conduct the electrical stimulus in an anterograde, retrograde or bidirectional manner.

Objective: To evaluate the correlation of AP location with the male and female genders and AP clinical presentation, whether manifest or concealed.

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Background And Objective: The increased use of epidural analgesia with catheter leads to the need to demonstrate the safety of this method and know the incidence of catheter colonization, inserted postoperatively for epidural analgesia, and the bacteria responsible for this colonization.

Methods: From November 2011 to April 2012, patients electively operated and maintained under epidural catheter for postoperative analgesia were evaluated. The catheter tip was collected for semiquantitative and qualitative microbiological analysis.

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Unlabelled: Pressure ulcers (PU) are a major reservoir of methicillin-resistant Staphylococcus aureus (MRSA) in hospitals. The objectives of this study were to estimate the prevalence of MRSA colonization in PU of hospitalized patients with Stage II or higher PU, to identify risk factors for colonization of these wounds, and to ascertain whether MRSA colonization of PU increases the risk of MRSA bacteremia.

Methods: This study was conducted at the Clinical Hospital of Federal University of Uberlandia, MG, Brazil.

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Background: Since 1991 several outbreaks of acute coccidioidomycosis (CM) were diagnosed in the semi-arid Northeast of Brazil, mainly related to disturbance of armadillo burrows caused by hunters while digging them for the capture of these animals. This activity causes dust contaminated with arthroconidia of Coccidioides posadasii, which, once inhaled, cause the mycosis. We report on the identification of C.

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Purpose: To assess the efficacy of needle revision using mitomycin C (MMC) for reviving failed filtering blebs during the late postoperative period and its safety for the corneal endothelium.

Design: Prospective interventional case series.

Participants: We recruited 125 eyes from 98 patients with uncontrolled glaucoma.

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Emergence of vancomycin-resistant bacteria is of concern. In an effort to reduce this danger, guidelines to ensure proper prescribing of vancomycin have been proposed by the Hospital Infections Control Practices Advisory Committee (HICPAC) of the Centers for Disease Control. To evaluate use of vancomycin at Uberlândia University Hospital in Brazil, each patient who received the drug during a 10 month period had nasal and rectal cultures done within 48 hours of initiation of therapy, then at weekly intervals until discharge.

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The seroprevalence of anti-hepatitis E virus (HEV) antibodies was investigated by enzyme immunoassay in 205 volunteer blood donors, 214 women who attended a center for anonymous testing for human immunodeficiency virus (HIV) infection, and 170 hospital employees in Campinas, a city in southeastern Brazil. The prevalence of anti-HEV antibodies ranged from 2.6% (3 of 117) in health care professionals to 17.

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