Publications by authors named "Fikre Enquesilassie"

Background: The risk factors for tuberculosis (TB) disease development in children remained understudied, particularly in low-income countries like Ethiopia. The objective of this study was to identify determinants of TB disease development in general and in relation to BCG vaccination in children in central Ethiopia.

Methods: We employed a 1:1 age-matched case-control design to compare the characteristics of children who developed TB (cases) with those who did not (controls).

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Background: One of the global key indicators for monitoring the implementation of the World Health Organization's End Tuberculosis (TB) Strategy is the treatment outcome rate.

Objective: This study aims to assess the magnitude of unfavorable treatment outcomes and estimate their relationship with baseline undernutrition and sustained undernutrition among children receiving TB treatment in central Ethiopia.

Methods: This retrospective cohort study included children treated for drug-susceptible TB between June 2014 and February 2022.

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Article Synopsis
  • The study focused on childhood tuberculosis (TB) in Ethiopia, aiming to analyze its epidemiology and identify factors that lead to death among treated children.
  • It involved a retrospective cohort of 640 children treated for TB from 2014 to 2022, revealing that significant predictors of death included HIV infection, undernutrition, being under 10 years old, and a history of relapsed TB.
  • The findings highlighted a concerning death rate among these children, especially those under two, pointing out that most contracted TB from the community rather than known household contacts.
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Introduction: Numerous studies have explored an effect of cigarette smoking on tuberculosis treatment outcomes but with dissimilar conclusions.

Objective: To determine the effect of cigarette smoking on tuberculosis treatment outcomes.

Methods: PubMed, Cochrane library and Google scholar databases were searched last on February 27, 2019.

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