Dyspnea in young subjects with congenital central hypoventilation syndrome.

Background: It has been stated that patients with congenital central hypoventilation syndrome (CCHS) do not perceive dyspnea, which could be related to defective CO chemosensitivity.

Methods: We retrospectively selected the data of six-minute walk tests (6-MWT, n = 30), cardiopulmonary exercise test (CPET, n = 5) of 30 subjects with CCHS (median age, 9.3 years, 17 females) who had both peripheral (controller loop gain, CG0) and central CO chemosensitivity (hyperoxic, hypercapnic response test [HHRT]) measurement.

Acute ethmoiditis complicated by intraorbital abscess, orbital cellulitis, and cerebral empyema in a 14-year-old girl.

We report the case of a 14-year-old girl with pain and protrusion of the left eye and treated with diclofenac. Clinical and paraclinical examinations revealed a cerebral empyema and a left retro-orbital abscess complicating an acute ethmoiditis. Parenteral antibiotic remains essential in the management of acute ethmoiditis to prevent complications.