Purpose Of Review: Here we highlight the significant contribution that genomics-based approaches have had on the field of research and the insights these approaches have generated into biology and transmission.
Recent Findings: There are advances in genomics, genetic manipulation, gene expression, and single-cell technologies. New and better genome sequences have revealed variable sub-telomeric gene families and genes under selection.
Parasites and their hosts are engaged in reciprocal coevolution that balances competing mechanisms of virulence, resistance, and evasion. This often leads to host specificity, but genomic reassortment between different strains can enable parasites to jump host barriers and conquer new niches. In the apicomplexan parasite , genetic exchange has been hypothesized to play a prominent role in adaptation to humans.
View Article and Find Full Text PDFParasites and their hosts are engaged in rapid coevolution that balances competing mechanisms of virulence, resistance, and evasion. This often leads to host specificity, but genomic reassortment between different strains can enable parasites to jump host barriers and conquer new niches. In the apicomplexan parasite genetic exchange has been hypothesized to play a prominent role in adaptation to humans.
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