Characterizing preferences of fishermen to inform decision-making: A case study of the Pacific halibut (Hippoglossus stenolepis) fishery off Alaska.

In fisheries management, ex-ante analysis of fishermen's preferences can provide reliable insights into specific characteristics of regulatory alternatives that are desirable, objectionable, or important, in the judgement of fishermen. This knowledge could facilitate consideration by fishery managers of additional regulatory alternatives with high likelihoods of meeting program objectives, minimal disruption to fishing operations and lifestyles, and high levels of acceptance and compliance from the fishing fleet. In this case study, we interviewed Pacific halibut fishermen (n = 76) in four communities across Southeast Alaska, to document their preferences about different types of data collection methods on their vessels.

Intestinal damage induced by zinc deficiency is associated with enhanced CuZn superoxide dismutase activity in rats: effect of dexamethasone or thyroxine treatment.

Zinc has a wide spectrum of biological activities and its deficiency has been related to various tissue dysfunctions and alterations of normal cell metabolism. Zinc also plays an important role in the antioxidant cellular defenses being a structural element of the non-mitochondrial form of the enzyme superoxide dismutase (CuZnSOD). We have already reported that Zn deficiency induces severe alterations in the rat intestine, that are reverted by treatment with dexamethasone (Dex) or thyroxine (T4).

Treatment of rats with dexamethasone or thyroxine reverses zinc deficiency-induced intestinal damage.

Structural and functional damage to the intestine and the potential beneficial effects of dexamethasone (Dex) and thyroxine (T4) were examined in zinc-deficient rats. Rats were assigned to zinc deficient (ZD), control (C) or pair-fed (PF ) groups and fed for 40 d a zinc deficient (1 mg/kg) diet (ZD rats) or a similar diet supplemented with 50 mg Zn/kg (C and PF rats). Some rats of the ZD group were treated for the last 10 d with low (250 mg/kg) or high (5 mg/kg) doses of Dex or with T4 (100 mg/kg).

[A prospective study on nephrotoxicity induced by continuous infusion of high-dose ifosfamide (15/m2)].

Background: A good response rate to high-dose ifosfamide (HDIFO) has been reported in metastatic osteosarcoma and soft tissue tumors. As standard dose of IFO (< 12 g/m2) can give several renal complications and patients previously treated with nephrotoxic drugs are at high risk of nephrotoxicity, a prospective study to evaluate the pattern of nephrotoxicity induced by HDIFO was carried out.

Methods: Twelve patients (11 metastatic osteosarcoma, 1 synovial sarcoma; mean age 17, R 14-34) were treated with 4 courses of HDIFO/ MESNA (15 g/m2, IV 5 day continuous infusion with bicarbonate and K supplements).

The role of corrected QT interval in the cardiologic follow-up of young patients treated with Adriamycin.

Unlabelled: The behavior over time of the corrected QT interval (QTc) in patients treated with Adriamycin (ADM) was evaluated in order to detect any possible correlations between the modifications of the QTc duration and the cardiac function of patients treated with different cumulative doses of ADM (360, 390, 480 mg/m2).

Patients And Methods: Electrocardiograms (ECGs) performed 2 months (178 patients), 1 year (65) and 3 years (43) after the completion of chemotherapy, were examined.

Results: after 2 months a prolonged QTc interval (> or = 0.

Proximal deep vein thrombosis: the use of the echoDoppler for diagnosis and therapeutic indications.

Our objective was to assess the impact of echo-Doppler technique on the diagnosis of Deep Vein Thrombosis (DVT) in major orthopedic surgery (80% of DVT diagnosed are asymptomatic). We therefore analyzed 200 consecutive pts submitted to elective surgery for total hip replacement. The postoperative echo-Doppler study indicated DVT in 13 pts: these pts underwent a postoperative lower limb phlebography.

High-dose methotrexate treatment and liver function in patients with osteosarcoma.

Objectives: To study the effects of short-term high-dose methotrexate therapy on liver function in patients with osteosarcoma.

Design: Open prospective study.

Setting: Department of Internal Medicine and Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy.

Electromagnetic fields in the treatment of postmenopausal osteoporosis: an experimental study conducted by densitometric, dry ash weight and metabolic analysis of bone tissue.

The authors conducted an experimental study on 32 female rats which had been castrated at 10 months of age in order to verify the ability of pulsating electromagnetic fields to prevent osteoporosis induced by surgical menopause. Two different values of intensity of PEMFs were used: 30 G and 70 G. After 4 months of treatment the following testing was done: monophotonic bone densitometry of the lumbar spine, quantitative measurement of the dry ash weight of the femurs, and hematochemical tests to evaluate bone metabolism.

[The oral strontium load test in the assessment of intestinal calcium absorption].

A close correlation between calcium and strontium intestinal absorption has been described. In this study, a test using Stable Strontium has been assessed in women without abnormal calcium or bone metabolism, with no history of drugs which might affect calcium or bone metabolism. Decreasing values of Strontium intestinal absorption, according to the length of the postmenopausal period, have been observed.

[Prevention of post-ovariectomy osteoporosis in the rat. Comparative study of synthetic salmon calcitonin and eel calcitonin aminosuberic analogue].

The authors evaluate the efficacy of salmon calcitonin and aminosuberic analogue of eel calcitonin in the prevention of post-oophorectomy osteoporosis in rats. Both drugs, administered at the same dosage, are equally effective in preventing oophorectomy bone loss in rats. Besides, plasma biochemical evaluations demonstrate that calcitonins reduce bone turnover in treated rats, compared with control oophorectomized ones.

Evaluation of an experimental model of osteoporosis induced in the female rat through ovariectomy.

The present paper intends to check the possibility of improving convenience of the osteoporosis model from ovariectomy in the rat by anticipating the operation to the 40th week rather than the 52nd week of age, thought by some authors to be the optimum model. To this end two parameters have been examined: 1. the bone mass variation determined with the vertebral photon densitometer and weighing of the femur ashes; 2.

[Effect of high and low doses of methotrexate (MTX) on bone mass in subjects treated for osteosarcoma of the limbs].

Twenty-three patients with highly malignant localized osteosarcoma receiving neoadjuvant chemotherapy with MTX randomly administered at high (7500 mg/m2) and low (750 mg/m2) doses underwent serial densitometric controls at the start of treatment and after 18 and 36 months. Increasing BMC levels at both examination points were observed in all subjects examined over time, but, contrary to findings in the control group, this increase was not statistically significant using the paired T test. Significantly lower BMC levels in relation to the control group were only found in the group treated with high doses of MTX at MDP but not PM.

[Ultrasound in the diagnosis of fragilitas ossium].

Recently, a proposal has been made to evaluate bone fragility in osteoporotic women by measuring ultrasound transmission velocity at the patella. Theoretically, sound transmission velocity depends on both bone mass and other factors which are not mass-dependent--e.g.

Evaluation of the relative rates of bone mineral content loss in postmenopause due to both estrogen deficiency and ageing.

To evaluate the relative rates of bone mineral content loss in postmenopause due to both estrogen deficiency and ageing, three groups of women were studied by computerized bone densitometry at the radius mid-point and at the distal point, modified according to the Abwrey technique. All women were in apparent good health and never had estrogen therapy. In the first group there were 64 women aged between 30 and 50 who were ovariectomized between 25 and 35 years of age.

The importance of urinary hydroxyproline and serumal osteocalcin in the evaluation of post-menopausal osteoporosis.

Forty-nine women aged 49 to 65 who had been in menopause for more than fifteen years were selected on the basis of densitometric data and clinical symptomatology. Twenty-four of these suffered from severe backaches and had a bone mineral content (B.M.

Contribution to the diagnostic study of pulmonary embolism occurring as a complication of operations for the insertion of hip prostheses.

The authors report the clinical, electrocardiographic and radiological aspects of pulmonary embolism as a post-operative complication which occurred in 46 patients after total hip replacement. They discuss the relative value of their findings in relation to arriving at a correct diagnosis, which they believe should be possible without recourse to more complicated procedures such as the use of contrast media radiography.

Thromboembolism in total hip replacement.

The efficacy of low dosage heparin in the prevention of pulmonary embolism has been assessed in a group of 177 "high risk" patients undergoing hip replacement operations compared with a control group of 236 "high risk" patients not so treated. The diagnosis of pulmonary embolism was made on the basis of the commonly accepted clinical signs and symptoms, confirmed by electrocardiography, chest radiography, serum enzymes, and blood gas analysis. Pulmonary embolism occurred in 9.

Full-lung tomograms and bone scanning in the initial work-up of patients with osteogenic sarcoma. A review of 126 cases.

The value of full-lung tomograms and of bone scanning in the initial work-up of patients with osteogenic sarcoma is evaluated in 126 consecutive cases observed at the Bone Tumor Center of the Istituto Ortopedico Rizzoli from July 1976 to December 1980. Full-lung tomograms and bone scanning showed unsuspected metastases in 3 patients and 2 patients respectively. False abnormal results were observed in 4 cases by tomography and in 3 cases by bone scan.

Thrombo-embolism as a complication of prosthetic replacement operations of the hip: prophylaxis with heparin at low doses.

A trial conducted in 183 high-risk patients who had had joint prosthesis operations showed that prophylaxis with Heparin reduces the frequency of pulmonary embolic complications and thrombophlebitis.

[The association of local radiation therapy and systemic chemotherapy in the treatment of clinically localized Ewing's sarcoma].

The results obtained in 12 cases of still clinically localized Ewing's sarcoma by associating radiation therapy of the primary focus with intermittent systematic chemotherapy are reported. Two of these patients presented pulmonary and bone metastases 12 and 14 months respectively after bioptic diagnosis while the remaining ten were in good health and free from metastasis at between 6 and 28 months (average 16 months) after biopsy. Although it is considered necessary to make further observations before the association's validity is certain, it is considered that on this basis and on the basis of the few cases reported in the literature than the association of rationally conducted systematic chemotherapy with local radiation therapy will extend the onset time of metastasis and so increase average survival in Ewing's sarcoma.