Publications by authors named "Figen Ozdemir"
Aim: the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene is of increasing interest in etiology and treatment of various neuropsychiatric disorders. The present study aimed at detecting the incidence of ACE gene I/D polymorphism in patients with schizophrenia living in the Eskisehir region (Turkey) and also at determining whether this illness could be associated to ACE gene I/D polymorphism and serum ACE concentrations.
Methods: in our study, genomic DNA was studied in a total of 237 individuals, 132 of them having been diagnosed as patients with schizophrenia and 105 of them being used as control subjects.
Background: Patients with pseudo-dementia are at particular risk of being labeled as Alzheimer dementia. We thus need better diagnostic methods. In this study, we evaluated the cerebral reactivity of the posterior cerebral arteries (PCAs) during visual stimulation by transcranial Doppler ultrasonography.
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- Schizophrenia is a severe neuropsychiatric disorder impacting 0.5-1% of the global population, characterized by increased dopamine activity and links to the DRD2 gene.
- Various studies examining the connection between dopamine activity and communication in cells have produced mixed results regarding schizophrenia's genetic aspects.
- A study involving 73 schizophrenic patients and 60 controls found no significant differences in the DRD2 gene -141C Ins/Del polymorphism frequencies or relationships between the gene and schizophrenia severity or types among participants.
Objective: To evaluate the absence and size of massa intermedia (MI), a midline thalamic structure, and its gender-specific alteration in patients with schizophrenia and bipolar disorder.
Methods: Thirty-five patients with schizophrenia (17 females and 18 males), 21 patients with bipolar disorder (15 females and 6 males) and 89 healthy controls (50 females and 39 males) were evaluated by magnetic resonance imaging. Thin-slice magnetic resonance images of the brain were evaluated.