Correlation between clinical parameters characterising peri-implant and periodontal health: a practice-based research in Spain in a series of patients with implants installed 4-5 years ago.

Objectives: To explore peri-implant health (and relation with periodontal status) 4-5 years after implant insertion.

Study Design: A practice-based dental research network multicentre study was performed in 11 Spanish centres. The first patient/month with implant insertion in 2004 was considered.

Comparison of clinical, radiographic, computed tomographic, and magnetic resonance imaging methods for early prediction of canine hip laxity and dysplasia.

The purpose of the study was to use two palpation methods (Bardens and Ortolani), a radiographic distraction view, three computed tomography (CT) measurements (dorsolateral subluxation score, the lateral center-edge angle, and acetabular ventroversion angle) and two magnetic resonance (MR) imaging hip studies (synovial fluid and acetabular depth indices) in the early monitoring of hip morphology and laxity in 7-9 week old puppies; and in a follow-up study to compare their accuracy in predicting later hip laxity and dysplasia. The MR imaging study was performed with the dog in dorsal recumbency and the CT study with the animal in a weight-bearing position. There was no association between clinical laxity with later hip laxity or dysplasia.

Bone formation following sinus grafting with autogenous bone-derived cells and bovine bone mineral in minipigs: preliminary findings.

Bone formation in a sinus grafted with a cell-free scaffold requires the presence of local progenitor cells that differentiate into osteoblasts. The purpose of this study was to examine the effect of culture expanded autogenous bone-derived cells (ABC) with bovine bone mineral (BBM) on bone formation after single-stage sinus grafting in minipigs. Bone biopsies from the iliac crest were harvested 4 weeks prior to sinus grafting and ABC were culture expanded in vitro.

Effect of platelet-released growth factors and collagen type I on osseous regeneration of mandibular defects. A pilot study in minipigs.

Objective: To study the effects of platelet-released growth factors (PRGF) and collagen type I on bone defect healing in minipig mandibles.

Material And Methods: In eight adult minipigs defects were trephined in the facial mandibular wall from extra-oral and filled with collagen+PRGF or with collagen alone. Control defects were left untreated.

Effects of fibrin sealant protein concentrate with and without platelet-released growth factors on bony healing of cortical mandibular defects. An experimental study in minipigs.

In this study, the effects of fibrin sealant protein concentrate (FSPC; from the Tissucol Kit, Baxter, Vienna, Austria) with and without platelet-released growth factors (PRGF) on bony healing of cortical mandibular defects were investigated. Defects made in the facial mandibular wall of eight adult minipigs with a hollow drill were filled with FSPC alone, a mix of FSPC+PRGF or left untreated as controls. The animals were killed 4 and 8 weeks later.

Enhanced bone-to-implant contact by platelet-released growth factors in mandibular cortical bone: a histomorphometric study in minipigs.

Purpose: To determine the effects of platelet-released growth factors (PRGF) on bone-to-implant contact (BIC) in minipig cortical bone.

Materials And Methods: In each of 8 adult minipigs, 2 implants were placed in the facial wall of the mandible, one implant with and one without PRGF. PRGF was defined as the supernatant from washed, thrombin-activated, allogenic, platelet-rich plasma cells obtained after centrifugation.

Sinus grafting with autogenous platelet-rich plasma and bovine hydroxyapatite. A histomorphometric study in minipigs.

In this study, bovine hydroxyapatite (HA) alone or in combination with activated platelet-rich plasma (PRP) was examined for its usefulness for single-stage sinus grafting in minipigs. In 12 adult minipigs, Schneider's membrane of 24 sinuses was elevated bilaterally through an extra-oral approach. The material was divided into two groups of 12 sinuses.

Experimental mandibular regeneration by distraction osteogenesis with submerged devices: preliminary results of a canine model.

The authors describe a new technique for reconstruction of mandibular body defects. The feasibility of distraction osteogenesis with submerged (internal) devices for reconstruction of segmental mandibular defects is investigated in an experiment with five adult dogs. A segmental mandibulectomy was performed on the horizontal ramus.