Chronic recurrent multifocal osteomyelitis (CRMO) is a rare but underdiagnosed, severe inflammatory bone disease that primarily affects children. It's typically characterized by bone pain, especially within the metaphysis of long bones, clavicles, and vertebrae, but it can present in any bone and with varied presentation, including extraosseous symptoms that may be associated with other autoimmune/inflammatory diseases. Chronic recurrent multifocal osteomyelitis is a sterile bone disease that does not typically have an infectious source.
View Article and Find Full Text PDFWhile hybridization was viewed as a hindrance to adaptation and speciation by early evolutionary biologists, recent studies have demonstrated the importance of hybridization in facilitating evolutionary processes. However, it is still not well-known what role spatial and temporal variation in natural selection play in the maintenance of naturally occurring hybrid zones. To identify whether hybridization is adaptive between two closely related monkeyflower species, and , we performed repeated reciprocal transplants between natural hybrid and pure species' populations.
View Article and Find Full Text PDFLymphoma is a well-known complication related to HIV infection; of these, non-Hodgkin lymphoma (NHL) is the most common subtype with Hodgkin lymphoma (HL) occurring less frequently. We present a rare case of a 35-year-old male with a history of HIV/AIDS well-controlled on antiretroviral therapy (ART) with an atypical HL presentation. He arrived at the emergency department with rectal bleeding, 30-pound unintentional weight loss, and subjective fever.
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