Dexmedetomidine pharmacokinetics in the obese.

Purpose: This study aims to characterize the influence of body weight and composition on the pharmacokinetics of dexmedetomidine.

Methods: Twenty obese patients and 20 non-obese patients scheduled for elective laparoscopic surgery were given dexmedetomidine infusion schemes. Venous blood samples were taken during and after dexmedetomidine administration.